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Fuel cells operating as an immunosensor for cancer biomarker screening

Ferreira, Nádia; Carneiro, Liliana; Pinto, Alexandra M. F. R.; Sales, M. Goreti F.

This work presents the first integration of antibodies into one of the electrodes of a passive direct methanol fuel cell (DMFC) to create an autonomous immunosensor for cancer antigen 15–3 (CA15-3). The anode of the fuel cell was first made of carbon cloth with carbon black, platinum and ruthenium nanoparticles and then modified with anti-CA15-3, while the cathode was made of carbon cloth with carbon black and ...


Fuel cells operating as an immunosensor for cancer biomarker screening

Ferreira, Nádia; Carneiro, Liliana; Pinto, Alexandra M. F. R.; Sales, M. G. F.

This work presents the first integration of antibodies into one of the electrodes of a passive direct methanol fuel cell (DMFC) to create an autonomous immunosensor for cancer antigen 153 (CA15-3). The anode of the fuel cell was first made of carbon cloth with carbon black, platinum and ruthenium nanoparticles and then modified with anti-CA15-3, while the cathode was made of carbon cloth with carbon black and p...


Development of an innovative flexible paper-based methanol fuel cell (PB-DMFC) ...

Carneiro, Liliana; Pinto, Alexandra M. F. R.; Sales, M. G. F.

This work describes for the first time a paper-based direct methanol fuel cell platform (PB-DMFC) that functions as an energy source and biosensor, assembled on a simple paper substrate for point-of-care (POC) applications, targeting sarcosine as proof-of-concept. Specifically, a methanol fuel cell strip was developed from a square of Whatman paper, acting as substrate. The paper strip was treated with an imper...


An all-in-one approach for self-powered sensing: a methanol fuel cell modified ...

Carneiro, Liliana; Pinto, Alexandra M. F. R.; Mendes, Adélio; Sales, M. G. F.

This work describes the development of an innovative electrochemical biosensor comprehending a passive direct methanol fuel cell (DMFC) assembly, modified by a layer of a molecularly imprinted polymer (MIP) on a carbon fabric anode electrode containing Pt/Ru nanoparticles, This MIP film was prepared from poly(3,4-ethylenedioxythiophene) (PEDOT) and polypyrrole (PPy) obtained by in situ electropolymerization of ...


A passive direct methanol fuel cell as transducer of an electrochemical sensor,...

Carneiro, Liliana; Ferreira, Nádia; Moreira, Ana; Pinto, Alexandra M. F. R.; Mendes, Adélio; Sales, M. G. F.

This work describes an electrochemical sensor with a biomimetic plastic antibody film for carcinoembryonic antigen (CEA, an important biomarker in colorectal cancer), integrated in the electrical circuit of a direct methanol fuel cell (DMFC), working in passive mode and used herein as power supply and signal transducer. In detail, the sensing layer for CEA consisted of a Fluorine-doped Tin Oxide (FTO) conductiv...


Autonomous biosensor for screening breast cancer biomarkers using passive Fuel ...

Ferreira, Nádia; Pinto, Alexandra M. F. R.; Sales, M. G. F.


A new vision for fuel cells: application in cancer biomarker screening

Carneiro, Liliana; Pinto, Alexandra M. F. R.; Sales, M. G. F.


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