INTRODUÇÃO O adenocarcinoma do pâncreas (PDAC) apresenta-se como um tumor sólido com prognóstico extremamente desfavorável, tendo uma sobrevida global (OS) aos 5 anos de aproximadamente 5%. Na doença metastizada, os esquemas de quimioterapia (QT) aprovados em primeira linha são variados, maioritariamente à base de platino ou gemcitabina. O índice de resposta inflamatória sistémica (SIRI) consiste num scor...
Cervical cancer (CC) is one of the acquired immunodeficiency syndrome (AIDS) defining diseases and the human immunodeficiency virus (HIV) infection is thought to relate with increased acute toxicity of chemoradiotherapy (CRT). We investigated the effect of HIV status in the incidence of neutropenia associated with cisplatin-based CRT for CC and its impact in treatment completion. This is a single-center retrosp...
To determine the prevalence of dysmenorrhea, limitations in daily living and health care use due to menstrual pain.Observational transversal study of 274 adolescents and young adults (age ≤ 26) who had menstruated in the six months prior to the study, assisted at a Primary Health Care Center. Data were obtained by a 24-item anonymous questionnaire, which included questions about socio-demographic variables, men...