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Withanolides from leaves of Nicandra physalodes

Carrero, Diego A. S.; Batista, Pedro H. J.; Souza, Luciana G. S.; Pinto, Francisco C. L.; Vasconcelos, Mayron A. de; Teixeira, Edson H.

Five new withanolides, designated as 15-oxo-nicaphysalin B, 6 β ,7 α -dihydroxynicandrenone 10, 24 α ,25 β -dihydroxy-nicandrenone-2 and a mixture of the epimers 17-(1 α /1 β -methylpropanone)- nicandrenone, in addition to six known others, were isolated from the leaf acetone extract from Nicandra physalodes . The complete structures of the five new withanolides, particularly their relative stereochemistries, w...

Date: 2018   |   Origin: Oasisbr

7-epi-griffonilide, a new lactone from Bauhinia pentandra: complete 1H and 13C ...

Almeida, Macia Cleane Soares de; Souza, Luciana G. S.; Ferreira, Daniele A.; Pinto, Francisco C. L.; Oliveira, Débora R. de; Santiago, Gilvandete M. P.

A new lactone, 7-epi-griffonilide (1), and six known compounds, 2, 3a - 3c, 4a and 4b, were isolated from the leaves of Bauhinia pentandra (Fabaceae). The structures elucidation of 1 and 2 were based on detailed 2D NMR techniques and spectral comparison with related compounds, leading to complete assignment of the 1H and 13C NMR spectra.

Date: 2017   |   Origin: Oasisbr

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