4 documents found, page 1 of 1
Petrosamine isolated from marine sponge Petrosia sp. demonstrates protection ag...
RIbeiro, Joana Francisca Marinho Parente; Araújo-Silva, Henrique; Fernandes, Mário; Silva, Joilna Alves; Pinto, Francisco das Chagas L.According to The World Alzheimer Report 2023 by Alzheimer’s Disease International (ADI) estimates that 33 to 38.5 million people worldwide suffer from Alzheimer’s Disease (AD). A crucial hallmark associated with this disease is associated with the deficiency of the brain neurotransmitter acetylcholine, due to an affected acetylcholinesterase (AChE) activity. Marine organisms synthesize several classes of compou...
Tropane alkaloids from the stem bark of Erythroxylum bezerrae
Brito, Luana San de O.; Pinto, Francisco das Chagas L.; Moraes Filho, Manoel Odorico de; Rocha, Danilo D.; Mendoza, Maria Fernanda M.Six previously undescribed tropane alkaloids, designated as erythrobezerrines A-F, were isolated from the EtOH extract from the stem bark of Erythroxylum bezerrae Plowman. Their structures were elucidated based on the interpretation of the NMR and MS data and in some instances, confirmed by X-ray diffraction analysis. The cytotoxicity of the isolated compounds was evaluated against the cancer cell lines L929, P...
Chemical constituents of Solanum buddleifolium Sendtn
Pinto, Francisco das Chagas L.; Torres, Maria da Conceição de Menezes; Silveira, Edilberto R.; Pessoa, Otília Deusdênia L.; Braz Filho, Raimundop. 1111-1115; Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-04-15T14:38:05Z No. of bitstreams: 1 jf401185y.pdf: 1278639 bytes, checksum: 177484a8161527544db4eecf3a06c912 (MD5); Made available in DSpace on 2014-04-15T14:38:05Z (GMT). No. of bitstreams: 1 jf401185y.pdf: 1278639 bytes, checksum: 177484a8161527544db4eecf3a06c912 (MD5) Previous issue date: 2013; The chemical investigation of the stem EtOH...
Glicoalcaloides antifúngicos, flavonoides e outros constituintes químicos de So...
Pinto, Francisco das Chagas L.; Uchoa, Daniel Esdras de Andrade; Silveira, Edilberto Rocha; Pessoa, Otília Deusdênia Loiola; Braz-Filho, RaimundoTwo glycoalkaloids: solamargine and solasonine; three flavonoids: tiliroside, 7-O-α-L-ramnopyranosyl-kaempferol and 3-O-[ß-D-glucopyranosyl-(1→6)-α-L-ramnopyranosyl]-7- O-α-L-ramnopyranosyl-kaempferol, in addition to the tripeptide Leu-Ile-Val, the aminoacid proline and the eicosanoic acid were isolated from Solanum asperum (Solanaceae). The structures of all compounds were determined by interpretation of their...