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Mutational profle of Brazilian lung adenocarcinoma unveils association of EGFR ...

Leal, Letícia Ferro; Paula, Flávia Escremim de; De Marchi, Pedro; Viana, Luciano de Souza; Pinto, Gustavo Dix Junqueira; Carlos, Carolina Dias

Lung cancer is the deadliest cancer worldwide. The mutational frequency of EGFR and KRAS genes in lung adenocarcinoma varies worldwide per ethnicity and smoking. The impact of EGFR and KRAS mutations in Brazilian lung cancer remains poorly explored. Thus, we investigated the frequency of EGFR and KRAS mutations in a large Brazilian series of lung adenocarcinoma together with patients' genetic ancestry, clinicop...

Date: 2019   |   Origin: RepositóriUM - Universidade do Minho
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