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Improving indoor air quality in a higher-education institution through biophili...

Idália da Gomes, Maria; Joanaz De Melo, Ana Maria Garcia Henriques Barreiros; Pinto, Iola; Rodrigues, Alexandra

Schools are vital infrastructures where students acquire essential skills and foster social values. Indoor air quality (IAQ) is of paramount importance in schools, given that students spend a considerable amount of time indoors. This study examines the influence of a natural green structure (NGS) on IAQ in an Eco-Campus classroom. The IAQ of a classroom with an NGS was compared to that of an adjacent classroom ...


Trends in COVID-19 patient characteristics and mortality throughout the pandemi...

Von Rekowski, Cristiana; Pinto, Iola; Henrique Fonseca, Tiago Alexandre; Araújo, Rúben Alexandre Dinis; Ferreira, Artur; Calado, Cecília; Bento, Luís

As SARS-CoV-2 continues to circulate globally and new variants emerge, it remains relevant to gather data on the affected patients’ clinical characteristics and outcomes to understand how individual factors and public health measures affect prognosis. Thus, we analyzed data of 870 ICU patients admitted for COVID-19 across two distinct phases of the pandemic: before and after the introduction of immunization. Ex...


An interactive dashboard for statistical analysis of intensive care unit COVID-...

Dias, Rúben; Ferreira, Artur; Pinto, Iola; Brás-Geraldes, Carlos; Von Rekowski, Cristiana; Bento, Luís

COVID-19 caused a pandemic, due to its ease of transmission and high number of infections. The evolution of the pandemic and its consequences for the mortality and morbidity of populations, especially the elderly, generated several scientific studies and many research projects. Among them, we have the Predictive Models of COVID-19 Outcomes for Higher Risk Patients Towards a Precision Medicine (PREMO) research p...


The characteristics and laboratory findings of SARS-CoV-2 infected patients dur...

Von Rekowski, Cristiana; Fonseca, Tiago AH; Araújo, Rúben; Brás-Geraldes, Carlos; Calado, Cecília; Bento, Luís; Pinto, Iola

Background and Objectives: Given the wide spectrum of clinical and laboratory manifestations of the coronavirus disease 2019 (COVID-19), it is imperative to identify potential contributing factors to patients’ outcomes. However, a limited number of studies have assessed how the different waves affected the progression of the disease, more so in Portugal. Therefore, our main purpose was to study the clinical and...


An Interactive Dashboard for Statistical Analysis of Intensive Care Unit COVID-...

Dias, Rúben; Ferreira, Artur; Pinto, Iola; Geraldes, Carlos; Von Rekowski, Cristiana; Bento, Luís

Background: COVID-19 caused a pandemic, due to its ease of transmission and high number of infections. The evolution of the pandemic and its consequences for the mortality and morbidity of populations, especially the elderly, generated several scientific studies and many research projects. Among them, we have the Predictive Models of COVID-19 Outcomes for Higher Risk Patients Towards a Precision Medicine (PREMO...


Laboratory biomarkers associated to death in the first three COVID-19 waves in ...

Von Rekowski, Cristiana; Fonseca, Tiago; Calado, Cecília; Bento, Luís; Pinto, Iola; Araújo, Rúben

Besides the pandemic being over, new SARS-CoV-2 lineages, and sub-lineages, still pose risks to global health. Thus, in this preliminary study, to better understand the characteristics of COVID-19 patients and the effect of certain hematologic biomarkers on their outcome, we analyzed data from 337 patients admitted to the ICU of a single-center hospital in Lisbon, Portugal, in the first three waves of the pande...


Detection of JCV or BKV viruria and viremia after kidney transplantation is not...

Querido, Sara; Weigert, Andre; Pinto, Iola; Papoila, Ana Luísa; Pessanha, Maria Ana; Gomes, Perpétua; Adragão, Teresa; Paixão, Paulo

Studies analyzing the relationship between BK polyomavirus (BKV) or JC polyomavirus (JCV) infection and kidney transplant (KT) long term clinical outcomes are scarce. Therefore, we evaluated this relationship in a single-center retrospective cohort of 288 KT patients followed for 45.4(27.5; 62.5) months. Detection of BKV viremia in two consecutive analyses led to discontinuation of antimetabolite and initiation...


Audiological biomarkers of tinnitus in an older Portuguese population

Haider, Haúla F.; Ribeiro, Diogo; Ribeiro, Sara F.; Trigueiros, Nuno; Caria, Helena; Borrego, Luís; Pinto, Iola; Papoila, Ana L.; Hoare, Derek J.

Tinnitus is a phantom sound perceived in the absence of external acoustic stimulation. It is described in a variety of ways (e.g., buzzing, ringing, and roaring) and can be a single sound or a combination of different sounds. Our study evaluated associations between audiological parameters and the presence or severity of tinnitus, to improve tinnitus diagnosis, treatment, and prognosis. Our sample included 122 ...


Impact of perioperative chemotherapy on postoperative morbidity after gastrecto...

Cabral, Francisco; Ramos, Paulo; Monteiro, Cecília; Casaca, Rui; Pinto, Iola; Abecasis, Nuno

Introduction: The use of perioperative chemotherapy (CT) in patients with advanced gastric carcinoma increases their overall survival. This therapy may also increase the number of patients with R0 resection. Potential drawbacks of this therapy, besides its toxicity, include increased surgical morbidity. Methods: We retrospectively evaluated the records of patients undergoing gastrectomy with curative intent, fo...


Complete pathological response (pCR) in gastroesophageal cancer: Correlation wi...

Cabral, Francisco; Cruz, A.; Casaca, R.; Monteiro, C.; Ramos, P.; Pedro, C.; Brandão, F.; Fonseca, R.; Ratão, P.; Saldado, L.; Pinto, Iola; Abecasis, N.

Purpose. - Neoadjuvant chemoradiotherapy (nCRT) followed by surgery in patients with resectable esophageal or esophagogastric junctional (GEJ) (Siewert I) cancer is associated with long term overall survival benefits. Up to one third of all patients submitted to nCRT present pathological complete response (pCR). F-18-fluorodeoxyglucose positron emission tomography with CT (F-18-FDG PET-CT) is an important tool ...


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