134 documents found, page 1 of 14

Chronicle of a Foretold Intersection: Mycoplasma pneumoniae and Brown- Séquard ...

Mycoplasma pneumoniae is a frequent cause of community-acquired respiratory infection in children but can also produce neurological complications. We report a 9-year-old child who developed neck pain followed by right hemiparesis and contralateral sensory loss, compatible with a Brown-Séquard-like presentation. Brain imaging was normal; spinal magnetic resonance imaging (MRI) showed a focal, right-lateral, C2–C...

Processo de transição no climatério - Estrategias do Enfermeiro Especialista em...

O climatério consiste num processo biológico marcado por alterações biopsicossociais que influenciam a qualidade de vida da mulher. Assim, torna-se fundamental identificar e responder às suas necessidades, promovendo a capacitação e facilitando uma transição saudável. Este relatório tem como objetivo compreender as necessidades, perceções e experiências das mulheres no climatério, identificando as estratégias d...

Dietary metabarcoding reveals the simplification of bird-pest interaction netwo...

Agriculture is vital for supporting human populations, but its intensification often leads to landscape homogenization and a decline in non-provisioning ecosystem services. Ecological intensification and multifunctional landscapes are suggested as nature-based alternatives to intensive agriculture, using ecological processes like natural pest regulation to maximize food production. Birds are recognized for thei...

Where do the children play? Spaces for/and children's participation in the outd...

This article presents the outline of an investigation that seeks to understand how children participate through outdoor play. Here we focus on the connection between participation and space. The study has its theoretical matrix in the Sociology of Childhood, with an emphasis on issues relating to children's participation. Our path is traced in the discussion about participation and action, based on the Conventi...

Benzo[a]phenoxazines as potential anti-inflammatory drugs

The chemical diversity of natural products provides a promising source of anti-inflammatory drugs, notably targeting COX-2, whose activity is associated with inflammatory processes and carcinogenesis. The COX-2 and LOX inhibitory capacity of several benzo[a]phenoxazines, N- and O-heterocyclic compounds, was studied. The kinetic assay results revealed that these molecules significantly inhibit COX-2 activity, hi...

Is it Guillain-Barré Syndrome with Extense Leptomenigeal Enhancement?

Urinary volatile metabolomic biomarkers for detection of bladder cancer

Background: Early detection of bladder cancer (BC) is necessary for improved outcomes, but current diagnostic methods may lack the necessary sensitivity. Metabolomics, particularly the analysis of urinary volatile organic compounds (VOCs), offers a promising, non-invasive approach to BC detection [1,2]. Objective: The study aimed to investigate potential urinary biomarkers for the detection and staging of ...

Chemical differences between alternative and traditional tobacco products

Background: Electronic cigarettes (E-cigs) and heated tobacco products (HTPs) have gained popularity as alternatives to traditional tobacco products (TTPs), claiming to reduce harm. The carcinogenic properties of chemicals in the smoke of TTPs are widely recognized. However, there is still an incomplete understanding of the different chemicals in E-cigs and HTPs and their toxicity to human cells [1]. Objec...

Metabolic profiling of renal cell carcinoma tissue using gas chromatography met...

Background: Renal cell carcinoma (RCC) is marked by dysregulation of angiogenesis, energy metabolism, and nutrient sensing pathways [1]. This diversity is an obstacle to achieving long-term responses to treatment, notwithstanding progress in targeted and immunotherapeutic drugs. Objective: This study aimed to characterise the metabolic dysregulations that occur in RCC tissue using a metabolomics approach. Metho...

Avaliação do endotélio corneano através de microscopia especular em participant...

Introdução: Apesar da integridade morfológica e funcional do endotélio corneano, essencial para a transparência corneana, ser afetada com a Diabetes Mellitus (DM) a sua relação com severidade de retinopatia diabética e presença de edema macular diabético não é clara. Objetivos: Avaliar as características morfológicas do endotélio corneano em doentes com Diabetes Mellitus Tipo 2 (DMT2) com diferentes perfis de r...