47 documents found, page 1 of 5
Persistent omphalomesenteric duct: a rare cause of acute intestinal volvulus in...
Gomes, Maria Miguel; Faria, Catarina; Alves, Manuela Costa; Silva, Ana Raquel; Pinto, Jorge Correia; Osório, AngélicaThis report describes the case of a 14-year-old male with a prior history of recurrent abdominal pain and two previous ”sub-occlusive” episodes. He presented at the Emergency Room with abdominal pain, emesis, abdominal distension, painful palpation, and signs of peritoneal irritation. Plain upright abdominal radiography suggested a distal small bowel obstruction. Exploratory laparoscopy showed a tubular structu...
Biomaterials and bioactive agents in spinal fusion
Duarte, Rui M.; Varanda, Pedro; Reis, R. L.; Duarte, Ana Rita C.; Pinto, Jorge CorreiaManagement of degenerative spine pathologies frequently leads to the need for spinal fusion (SF), where bone growth is induced toward stabilization of the interventioned spine. Autologous bone graft (ABG) remains the gold-standard inducer, whereas new bone graft substitutes attempt to achieve effective de novo bone formation and solid fusion. Limited fusion outcomes have driven motivation for more sophisticated...
Retinoic acid regulates avian lung branching through a molecular network
Silva, Hugo Fernandes; Cunha, Patrícia Vaz; Barbosa, Violina Baranauskaite; Gonçalves, Carla Silva; Pinto, Jorge Correia; Moura, Rute S.Retinoic acid (RA) is of major importance during vertebrate embryonic development and its levels need to be strictly regulated otherwise congenital malformations will develop. Through the action of specific nuclear receptors, named RAR/RXR, RA regulates the expression of genes that eventually influence proliferation and tissue patterning. RA has been described as crucial for different stages of mammalian lung m...
DERRAME PLEURAL NUMA POPULAÇÃO PEDIÁTRICA
Baptista, Vera; Moreira, Carla; Pinto, Jorge Correia; Gonçalves, AugustaIntrodução: o derrame pleural é uma complicação da pneu- monia que aumenta a sua morbilidade. Pretendemos descrever as características clínicas, estratégias diagnósticas e terapêutica do derrame pleural parapneumónico numa população pediátrica no hospital de Braga. Método: análise retrospetiva dos internamentos num período de 5 anos (2010-2015). Resultados: foram diagnosticados 50 derrames pleurais, com distrib...
Acute alithiasic cholecystitis and human herpes virus type-6 infection: first case
Gomes, Maria Miguel; Antunes, Henedina; Lobo, Ana Luísa; Branca, Fernando; Pinto, Jorge Correia; Pinto, João MoreiraA three-year-old male child presented with erythematous maculopapular nonpruritic generalized rash, poor feeding, vomiting, and cramping generalized abdominal pain. He was previously healthy and there was no family history of immunologic or other diseases. On examination he was afebrile, hemodynamically stable, with painful palpation of the right upper quadrant and positive Murphy's sign. Laboratory tests revea...
Characterization of miRNA processing machinery in the embryonic chick lung
Moura, Rute S.; Cunha, Patrícia Vaz; Gonçalves, Carla Silva; Pinto, Jorge CorreiaLung development is a very complex process that relies on the interaction of several signaling pathways that are controlled by precise regulatory mechanisms. Recently, microRNAs (miRNAs), small non-coding regulatory RNAs, have emerged as new players involved in gene expression regulation controlling several biological processes, such as cellular differentiation, apoptosis and organogenesis, in both developmenta...
Neuroendocrine factors regulate retinoic acid receptors in normal and hypoplast...
Terra, Patrícia Daniela Pereira; Moura, Rute S.; Silva, Cristina Nogueira; Pinto, Jorge CorreiaCongenital diaphragmatic hernia (CDH) is characterised by a spectrum of lung hypoplasia and consequent pulmonary hypertension, leading to high morbidity and mortality rates. Moreover, CDH has been associated with an increase in the levels of pulmonary neuroendocrine factors, such as bombesin and ghrelin, and a decrease in the action of retinoic acid (RA). The present study aimed to elucidate the interaction bet...
A novel method of full-thickness bladder closure with an endoscopic suturing ma...
Oliveira, Carlos; Autorino, Riccardo; Ferreira, Carlos; Cicione, Antonio; Damiano, Rocco; De Sio, Marco; Pinto, Jorge CorreiaObjective To assess the feasibility of a pure endoscopic closure method for vesical perforations using fully absorbable material. Materials and methods A pilot experimental study was performed in 8 anesthetized female pigs. Four 10mm and four 20mm endoscopic full thickness cystotomies were created. An endoscopic suturing machine (RD 180®, LSI solutions®) was deployed through the working channel of a cystoscope ...
Finite element analysis of pectus carinatum surgical correction via a minimally...
Neves, Sara C.; Pinho, A. C. Marques de; Fonseca, Jaime C.; Rodrigues, Nuno F.; Coelho, Tiago Henriques; Pinto, Jorge Correia; Vilaça, João L.Pectus carinatum (PC) is a chest deformity caused by a disproportionate growth of the costal cartilages compared to the bony thoracic skeleton, pulling the sternum towards, which leads to its protrusion. There has been a growing interest on using the ‘reversed Nuss’ technique as a minimally invasive procedure for PC surgical correction. A corrective bar is introduced between the skin and the thoracic cage and p...
Scarless laparoscopic repair of epigastric hernia in children
Pinto, Jorge Correia; Pinto, João MoreiraBackground Despite the small size of the incision, the scar left by open repair of epigastric hernia in children is unaesthetic. Few laparoscopic approaches to epigastric hernia repair have been previously proposed, but none has gain wide acceptance from pediatric surgeons. In this study, we present our experience with a scarless laparo- scopic approach using a percutaneous suturing technique for epigastric her...