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MPO interacts with hRSV particles, contributing to the virucidal effects of NET...

Pinto, Leonardo da Silva; Junior, Ronaldo Silva Alves; Lopes, Bruno Rafael Pereira; Silva, Gabriel Soares da; Menezes, Gabriela de Lima; Moreira, Pedro

Human Respiratory syncytial virus (hRSV) mainly affects immunosuppressed patients requiring hospitalization. No specific treatment is financially accessible, and available vaccines do not cover all risk groups. During hRSV infection, there is a robust neutrophilic influx into the airways. hRSV-activated neutrophils release substantial neutrophil extracellular traps (NETs) in lung tissue, comprising DNA, histone...


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