Background/Objectives: This study aimed to assess the acute effects of two isoenergetic but micronutrient-diverse meals-a Mediterranean-like meal (MdM) and a fast food-like meal (FFM)-on the autonomic nervous system (ANS), lung function, and airway inflammation response. Methods: Forty-six participants were enrolled in a randomized crossover clinical trial, consuming two isoenergetic meals: FFM (burger, fries, ...
A viabilidade da muografia como técnica de sondagem tem sido demonstrada em diversos trabalhos ao redor do mundo, desde os seus primeiros passos. A muografia com muógrafos em ambiente subterrâneo tem um lado fácil devido à ausência da radiação de fundo, mas, por outro lado, o fluxo de muões é muito menor em comparação com o que é medido na superfície. É uma questão de condições geológicas e subterrâneas, deteto...
Background: Cancer is associated with high mortality rates and its incidence worldwide is increasing significantly [1]. Several therapeutic strategies have been used in cancer therapy such as microtu-bule-targeting agents [2]. However, these drugs are highly toxic and are associated with high tumor resistance, making their long-term use unfeasible [3,4]. Therefore, new small molecules that can overcome the disa...
Background: The incidence of thyroid carcinoma (TC) in human population has been increasing worldwide, and it was estimated an incidence of 2.1% of cancer new cases in 2019 [1]. A smaller incidence is reported for canine population (1.1%) in 1995-2005 [2]. Diagnosis, prognosis, and management of human TC rely on mutation screening of BRAF, RAS genes, and TERT promoter. BRAF, NRAS, HRAS, and KRAS encode proteins...
Objective: Aspergillosis diagnosis depends on the detection of Aspergillus in biological samples ─ usually using cultural and immunoenzyme techniques ─ but their sensitivity and specificity varies. We aimed to study the prevalence of Aspergillus in patients at higher risk of chronic pulmonary aspergillosis (i.e., HIV-infected patients and individuals with active or previous tuberculosis), and to determine the p...
The LouMu team joins together specialists in particle detectors and in cosmic ray analyses, geophysicists and science communicators to muograph an underground gallery of an old mine, now open to visitors of a science museum. The muon telescope is made of Resistive Plate Chambers (RPCs) developed to operate stably and with low consumption at remote locations, and it has been tested in the Coimbra University, bef...
The solution to challenges in aeronautics involves shifting traditional learning and development into reskilling and upskilling. However, some see it as a responsibility of industries, others as a responsibility of educational institutes, and some others as a responsibility of workers themselves. We review each stakeholder’s role, importance, and actions to take, applied to the aeronautics sector. The pathway t...
Understanding how marine fish early-life history is affected in the long-term by environmental and oceanographic factors is fundamental given its importance to population dynamics and connectivity. This work aimed at determining the influence of these processes on the interannual variability in hatch day and early-life growth patterns of European seabass, over a seven-year period (2011-2017) in the Atlantic Ibe...
Infectious diseases, such as tuberculosis (TB) and the novel coronavirus (COVID-19) relate to environmental factors, understanding of which is essential to inform policy and practice and tackle them effectively. The review follows the conceptual framework offered by the World Health Organization Commission on Social Determinants of Health (defined as "all those material, psychological and behavioural circumstan...