36 documents found, page 1 of 4
Current Therapeutic Strategies for Burning Mouth Syndrome: Critical Review
Oliveira, Diva; Mottola, Carla; Pinto, Margarida; Lucas, PauloBurning mouth syndrome (BMS) is a medical condition with a complex and multifactorial etiology. It is characterized by a burning sensation, a dysaesthetic sensation, and pain in the tongue and/or oral mucosa. Since the BMS etiology is unknown, its treatment is a real challenge. This review aims to discuss the efficacy of the various therapeutic options currently available for BMS.This review was performed by se...
Emergence of KPC-3- and OXA-181-producing ST13 and ST17 Klebsiella pneumoniae i...
Elias, Rita; Spadar, Anton; Hendrickx, Antoni P A; Bonnin, Remy A; Dortet, Laurent; Pinto, Margarida; Phelan, Jody E; Portugal, Isabel; Campino, SusanaBackground Carbapenem-resistant Klebsiella pneumoniae (CRKP) strains are of particular concern, especially strains with mobilizable carbapenemase genes such as blaKPC, blaNDM or blaOXA-48, given that carbapenems are usually the last line drugs in the β-lactam class and, resistance to this sub-class is associated with increased mortality and frequently co-occurs with resistance to other antimicrobial classes. Ob...
Characterization of play, sleep, and behavior in preschool-aged children
Bragança, Raquel Lopes; Pinto, Margarida; Nogueira, Mayara; Ferreira, Margarida; Mota, Bárbara; Lourenço, Lara; Pinto, FátimaIntroduction: Playing is a fundamental activity of childhood. The primary goal of this study was to characterize the playing habits of Portuguese children aged between three and five years old. The secondary goals were to investigate children’s sleeping habits, audiovisual media exposure, and behavior, as well as caregivers´ perception of these. Material and methods: Observational study based on the application...
Characterization of play, sleep, and behavior in preschool-aged children
Fernandes Bragança Oliveira, Raquel; Pinto, Margarida; Nogueira, Mayara; Ferreira, Margarida; Mota, Bárbara; Lourenço, Lara; Pinto, FátimaIntroduction: Playing is a fundamental activity of childhood. The primary goal of this study was to characterize the playing habits of Portuguese children aged between three and five years old. The secondary goals were to investigate children’s sleeping habits, audiovisual media exposure, and behavior, as well as caregivers ́ perception of these.Material and methods: Observational study based on the application...
A phylogenomic approach for the analysis of colistin resistance-associated gene...
Elias, Rita; Spadar, Anton; Phelan, Jody; Melo-Cristino, José; Lito, Luís; Pinto, Margarida; Gonçalves, Luísa; Campino, Susana; Clark, Taane G.The emergence of carbapenemase-producing Klebsiella pneumoniae strains has triggered the use of old antibiotics such as colistin. This is driving the emergence of colistin resistance in multidrug-resistant strains that underlie life-threatening infections. This study analyses the mutational diversity of 22 genes associated with colistin resistance in 140 K. pneumoniae clinical isolates integrated in a high-reso...
Genomic epidemiological analysis of Klebsiella pneumoniae from Portuguese hospi...
Spadar, Anton; Phelan, Jody; Elias, Rita; Modesto, Ana; Caneiras, Cátia; Marques, Cátia; Lito, Luís; Pinto, Margarida; Cavaco‑Silva, PatríciaKlebsiella pneumoniae (Kp) bacteria are an increasing threat to public health and represent one of the most concerning pathogens involved in life-threatening infections and antimicrobial resistance (AMR). To understand the epidemiology of AMR of Kp in Portugal, we analysed whole genome sequencing, susceptibility testing and other meta data on 509 isolates collected nationwide from 16 hospitals and environmental...
A phylogenomic approach for the analysis of colistin resistance-associated gene...
Elias, Rita; Spadar, Anton; Phelan, Jody; Melo-Cristino, José; Lito, Luís; Pinto, Margarida; Gonçalves, Luísa; Campino, Susana; Clark, TaaneThe emergence of carbapenemase-producing Klebsiella pneumoniae strains has triggered the use of old antibiotics such as colistin. This is driving the emergence of colistin resistance in multidrug-resistant strains that underlie life-threatening infections. This study analyses the mutational diversity of 22 genes associated with colistin resistance in 140 K. pneumoniae clinical isolates integrated in a high-reso...
Genomic epidemiological analysis of Klebsiella pneumoniae from Portuguese hospi...
Spadar, Anton; Phelan, Jody; Elias, Rita; Modesto, Ana; Caneiras, Cátia; Marques, Cátia; Lito, Luís; Pinto, Margarida; Cavaco-Silva, PatríciaKlebsiella pneumoniae (Kp) bacteria are an increasing threat to public health and represent one of the most concerning pathogens involved in life-threatening infections and antimicrobial resistance (AMR). To understand the epidemiology of AMR of Kp in Portugal, we analysed whole genome sequencing, susceptibility testing and other meta data on 509 isolates collected nationwide from 16 hospitals and environmental...
As vivências e perceções da comunidade cigana no seu processo de realojamento
Pinto, Margarida; Monteiro, DanielaIntervenção Social. ISSN 0874-1611. N. 57-58 (2021).; O presente estudo aborda o realojamento da comunidade cigana (que residia no acampamento da Barragem de Bagaúste) no Bairro das Alagoas (Peso da Régua), e, tem como objetivo compreender o processo de realojamento a partir das suas vivências e perceções, particularmente, nas seguintes dimensões: 1) na transição entre o acampamento e o Bairro Social, 2) no aco...
Rifampicin-Resistant Serotype B Neisseria meningitidis: First Case in Portugal
Silva, Cláudia; Silva, Tiago; Candeias, Flora; Pinto, Margarida; Simões, Maria João; Brito, Maria JoãoSem abstract; Sem abstract