4 documents found, page 1 of 1
3-bromopyruvate suppresses the malignant phenotype of vemurafenib-resistant mel...
Vital, Patrik da Silva; Bonatelli, Murilo; Dias, Marina Pereira; Salis, Larissa Vedovato Vilela de; Pinto, Mariana Tomazini; Baltazar, Fátima(1) <i>BRAF</i> mutations are associated with high mortality and are a substantial factor in therapeutic decisions. Therapies targeting <i>BRAF</i>-mutated tumors, such as vemurafenib (PLX), have significantly improved the overall survival of melanoma patients. However, patient relapse and low response rates remain challenging, even with contemporary therapeutic alternatives. Highly proliferative tumors often r...
Short Communication: Human Bone Marrow Stromal Cells Exhibit Immunosuppressive ...
Rodrigues, Evandra Strazza; De MacEdo, Mayra Dorigan; Orellana, Maristela Delgado; Takayanagui, Osvaldo Massaiti; Palma, Patrícia Vianna BoniniMade available in DSpace on 2019-10-06T15:32:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-02-01; Human multipotent mesenchymal stromal cells (MSCs) display immunoregulatory functions that can modulate innate and adaptive cellular immune responses. The suppressive and immunomodulatory activities of MSCs occur through the action of soluble factors that are constitutively produced and released by thes...
FBXW7 circular RNA repress glioma tumorigenesis
Pinto, Mariana Tomazini; Reis, R. M.
HTLV-1/2 seroprevalence and coinfection rate in Brazilian first-time blood dono...
Pinto, Mariana Tomazini; Rodrigues, Evandra Strazza; Malta, Tathiane Maistro; Azevedo, Rochele; Takayanagui, Osvaldo MassaitiThe seroprevalence and geographic distribution of HTLV-1/2 among blood donors are extremely important to transfusion services. We evaluated the seroprevalence of HTLV-1/2 infection among first-time blood donor candidates in Ribeirão Preto city and region. From January 2000 to December 2010, 1,038,489 blood donations were obtained and 301,470 were first-time blood donations. All samples were screened with serolo...