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Cisatracúrio – Um Relaxante Neuromuscular “Seguro”?

Gonçalves, T; Pita, JS; Pinto, N; Ornelas, C; Leiria-Pinto, P

Os agentes anestésicos representam uma causa importante de anafilaxia a fármacos, sendo os relaxantes neuromusculares (RNM) dos principais responsáveis pelos casos de anafilaxia perioperatória. O cisatracúrio é o RNM mais recente, sendo um estereoisómero do atracúrio que se acreditava não ter potencial de libertação de histamina e, consequentemente, causar menos reações alérgicas do que os outros RNM. No entant...


Cross-Cultural Validation of the Portuguese from Portugal Version of the Test f...

Leiria-Pinto, P; Marques, J; Finelli, E; Alves, C; Alves, M; Trincão, D; Pinto, N; Carreiro-Martins, P; Papoila, AL; Neuparth, N

Introduction. The Test for Respiratory and Asthma Control in Kids (TRACK) is a tool to assess asthma control in preschool children. This study aims to validate the Portuguese from Portugal version of the TRACK questionnaire. Methods. A prospective cohort study was carried out to assess their psychometric characteristics. Caregivers of 141 children under age 5 with asthma symptoms were enrolled. Results. Interna...


Validation of App and Phone Versions of the Control of Allergic Rhinitis and As...

Jácome, C; Pereira, AM; Almeida, R; Amaral, R; Correia, MA; Mendes, S; Vieira-Marques, P; Ferreira, JA; Lopes, I; Gomes, J; Vidal, C; López Freire, S


Feasibility and Acceptability of an Asthma App to Monitor Medication Adherence:...

Jácome, C; Almeida, R; Pereira, AM; Amaral, R; Mendes, S; Alves-Correia, M; Vidal, C; López Freire, S; Méndez Brea, P; Araújo, L; Couto, M

Background: Poor medication adherence is a major challenge in asthma, and objective assessment of inhaler adherence is needed. The InspirerMundi app aims to monitor adherence while providing a positive experience through gamification and social support. Objective: This study aimed to evaluate the feasibility and acceptability of the InspirerMundi app to monitor medication adherence in adolescents and adults wit...

Date: 2021   |   Origin: Saúde - CUF

Monitoring Adherence to Asthma Inhalers Using the InspirerMundi App: Analysis o...

Jácome, C; Almeida, R; Pereira, AM; Amaral, R; Vieira-Marques, P; Mendes, S; Alves-Correia, M; Ferreira, JA; Lopes, I; Gomes, J; Araújo, L; Couto, M

Background: Poor medication adherence is a major challenge in asthma and objective assessment of inhaler adherence is needed. InspirerMundi app aims to monitor inhaler adherence while turning it into a positive experience through gamification and social support. Objective: We assessed the medium-term feasibility of the InspirerMundi app to monitor inhaler adherence in real-world patients with persistent asthma ...


Feasibility and Acceptability of an Asthma App to Monitor Medication Adherence:...

Jácome, C; Almeida, R; Pereira, AM; Amaral, R; Mendes, S; Alves-Correia, M; Vidal, C; López Freire, S; Méndez Brea, P; Araújo, L; Couto, M

Background: Poor medication adherence is a major challenge in asthma, and objective assessment of inhaler adherence is needed. The InspirerMundi app aims to monitor adherence while providing a positive experience through gamification and social support. Objective: This study aimed to evaluate the feasibility and acceptability of the InspirerMundi app to monitor medication adherence in adolescents and adults wit...


Influence of PICALM and CLU risk variants on beta EEG activity in Alzheimer’s d...

Maturana-Candelas, A; Gómez, C; Poza, J; Rodríguez-González, V; Pablo, VGd; Lopes, AM; Pinto, N; Hornero, R

PICALM and CLU genes have been linked to alterations in brain biochemical processes that may have an impact on Alzheimer’s disease (AD) development and neurophysiological dynamics. The aim of this study is to analyze the relationship between the electroencephalographic (EEG) activity and the PICALM and CLU alleles described as conferring risk or protective effects on AD patients and healthy controls. For this p...


4specid: Reference dna libraries auditing and annotation system for forensic ap...

Neto, L; Pinto, N; Proença, A; Amorim, A; Conde-Sousa, E

Forensic genetics is a fast-growing field that frequently requires DNA-based taxonomy, namely, when evidence are parts of specimens, often highly processed in food, potions, or ointments. Reference DNA-sequences libraries, such as BOLD or GenBank, are imperative tools for taxonomic assignment, particularly when morphology is inadequate for classification. The auditing and cura- tion of these datasets require re...


Apoe variants in an iberian alzheimer cohort detected through an optimized sang...

González, RD; Gomes, I; Gomes, C; Rocha, R; Durães, L; Sousa, P; Figueruelo, M; Rodríguez, M; Pita, C; Hornero, R; Gómez, C; Lopes, AM; Pinto, N

The primary genetic risk factor for late onset Alzheimer’s disease (LOAD) is the APOE4 allele of Apolipoprotein E (APOE) gene. The three most common variants of APOE are determined by single nucleotide polymorphisms (SNPs) rs429358 and rs7412. Our aim was to estimate allele and genotype frequencies of APOE variants in an Iberian cohort, thus helping to understand differences in APOE-related LOAD risk observed a...


Relationship between the presence of the ApoE e4 allele and EEG complexity alon...

Pablo, VGD; Gómez, C; Poza, J; Maturana-Candelas, A; Martins, S; Gomes, I; Lopes, AM; Pinto, N; Hornero, R

Alzheimer’s disease (AD) is the most prevalent cause of dementia, being considered a major health problem, especially in developed countries. Late-onset AD is the most common form of the disease, with symptoms appearing after 65 years old. Genetic determinants of AD risk are vastly unknown, though, e4 allele of the ApoE gene has been reported as the strongest genetic risk factor for AD. The objective of this st...


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