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Cultural adaptation for the portuguese pediatric population of the “AQUA” Quest...

Chantre, Tiago; Coelho, Pedro Simão; Pinto, Paula Leiria; Horta, Luís; Alpoim Moreira, Inês; Sousa, Herédio

Introduction - Respiratory symptoms and allergic diseases remain under-diagnosed both in the general population and in athletes. The Allergy Questionnaire for Athletes (AQUA), for screening these pathologies, has been validated and translated into Portuguese only for athletes age 16 years or over. Objectives - This work aims to culturally adapt the AQUA questionnaire into the Portuguese pediatric population, fo...


Successful off-label use of omalizumab in a child with chronic spontaneous urti...

Gonçalves, Tânia; Coutinho, Iolanda Alen; Pita, Joana Sofia; Pinto, Paula Leiria

Omalizumab is approved as third-line therapy for patients older than 12 years with antihistamine-refractory chronic spontaneous urticaria. The authors present the case of an eight-year-old boy with a history of migratory maculopapular skin lesions, arthralgias, and conjunctival hyperemia. Laboratory findings were unremarkable. Skin biopsy was consistent with urticaria. Treatment with oral betamethasone and quad...


Profiling Persistent Asthma Phenotypes in Adolescents: A Longitudinal Diagnosti...

Amaral, Rita; Jácome, Cristina; Almeida, Rute; Pereira, Ana Margarida; Alves-Correia, Magna; Mendes, Sandra; Rodrigues, José Carlos Cidrais

We aimed to identify persistent asthma phenotypes among adolescents and to evaluate longitudinally asthma-related outcomes across phenotypes. Adolescents (13-17 years) from the prospective, observational, and multicenter INSPIRERS studies, conducted in Portugal and Spain, were included (n = 162). Latent class analysis was applied to demographic, environmental, and clinical variables, collected at a baseline med...


Profiling Persistent Asthma Phenotypes in Adolescents: A Longitudinal Diagnosti...

Amaral, Rita; Jácome, Cristina; Almeida, Rute; Pereira, Ana Margarida; Alves-Correia, Magna; Mendes, Sandra; Rodrigues, José Carlos Cidrais

We aimed to identify persistent asthma phenotypes among adolescents and to evaluate longitudinally asthma-related outcomes across phenotypes. Adolescents (13-17 years) from the prospective, observational, and multicenter INSPIRERS studies, conducted in Portugal and Spain, were included (n = 162). Latent class analysis was applied to demographic, environmental, and clinical variables, collected at a baseline med...


Feasibility and acceptability of an asthma app to monitor medication adherence:...

Jácome, Cristina; Almeida, Rute; Pereira, Ana Margarida; Amaral, Rita; Mendes, Sandra; Alves-Correia, Magna; Vidal, Carmen; Freire, Sara López

Poor medication adherence is a major challenge in asthma, and objective assessment of inhaler adherence is needed. The InspirerMundi app aims to monitor adherence while providing a positive experience through gamification and social support. This study aimed to evaluate the feasibility and acceptability of the InspirerMundi app to monitor medication adherence in adolescents and adults with persistent asthma (tr...


Feasibility of a mobile app to improve inhaler adherence in real‐world patients...

Jácome, Cristina; Rute, Almeida; Amaral, Rita; Pereira, Ana Margarida; Vidal, Carmen; Freire, Sara Lopéz; Mendez Brea, Paula; Antolín- Amerigo, Dario

InspirerMundi app aims to transform adherence into a positive experience through gamification and social support, while allowing objective monitoring of inhaler adherence. This study assessed the feasibility of the app in adolescents and adults with persistent asthma.


ENT manifestation in children with Eosinophilic Esophagitis

Bento, Margarida Lagarto; Araújo, Joana Ximenes; Lobato, Mariana; Marques, João Gaspar; Moreira, Inês; Pinto, Paula Leiria; Cabral, José; Seixas, João

Objective: Characterize a population of children with Eosinophilic Esophagitis (EoE), highlighting their symptoms, ENT physical examination and previous medical history.  Material and Methods: Cross-sectional observational study of children aged 6 to 17 years, diagnosed with EoE, until January 2019. A clinical observation protocol was applied to every child.  Results: Fifteen children were included. The majorit...


The portuguese severe asthma registry : development, features, and data sharing...

Sousa, Ana Sá; Fonseca, João Almeida; Pereira, Ana Margarida; Ferreira, Ana; Arrobas, Ana; Mendes, Ana; Drummond, Marta; Videira, Wanda; Costa, Tiago

The Portuguese Severe Asthma Registry (Registo de Asma Grave Portugal, RAG) was developed by an open collaborative network of asthma specialists. RAG collects data from adults and pediatric severe asthma patients that despite treatment optimization and adequate management of comorbidities require step 4/5 treatment according to GINA recommendations. In this paper, we describe the development and implementation ...


Food protein-induced enterocolitis syndrome: a rare etiology

Janeiro, Maria Carlos; Costa, Cátia Alves; Prates, Sara; Pinto, Paula Leiria

Introduction: Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E mediated gastrointestinal food hypersensitivity, probably mediated by cells. The pathophysiological mechanism remains unclear. Cow’s milk and cereals are among the most common causes of FPIES. The diagnosis is based on clinical history. Case description: We report a rare case of enterocolitis with potato in an infant wit...


Measles, mumps and rubella vaccination in children with suspected egg allergy

Rosa, Sónia; Ribeiro, Filipa; Pinto, Paula Leiria

The General Directorate for Health (DGS) has published a recommendation for the administration of measles, mumps, rubella vaccine (MMR) in hospital for patients with a history of anaphylaxis due to egg allergy, previous reaction to MMR, and uncontrolled asthma in patients with documented egg allergy. Objective: To characterize the population referred to hospital for MMR administration regarding compliance with ...


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