2 documents found, page 1 of 1
Anthelmintic, Antibacterial and Cytotoxicity Activity of Imidazole Alkaloids fr...
Rocha, Jefferson A.; Andrade, Ivanilza M.; Véras, Leiz M.C.; Quelemes, Patrick V.; Lima, David F.; Soares, Maria J.S.; Pinto, Pedro L.S.; Mayo, Simon J.Pilocarpus microphyllus Stapf ex Wardlew (Rutaceae), popularly known as jaborandi, is a plant native to the northern and northeastern macroregions of Brazil. Several alkaloids from this species have been isolated. There are few reports of antibacterial and anthelmintic activities for these compounds. In this work, we report the antibacterial and anthelmintic activity of five alkaloids found in P. microphyllus l...
Antischistosomal activity of the terpene nerolidol
Silva, Marcos P.N.; Oliveira, George L.S.; Carvalho, Rusbene B.F. de; Sousa, Damião P. de; Freitas, Rivelilson M.; Pinto, Pedro L.S.; Moraes, Josué deSchistosomiasis is a neglected tropical disease that affects hundreds of millions of people worldwide. Since the treatment of this disease currently relies on a single drug, praziquantel, new and safe schistosomicidal agents are urgently required. Nerolidol, a sesquiterpene present in the essential oils of several plants, is found in many foods and was approved by the U.S. Food and Drug Administration. In this ...