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Proinflammatory and anti-inflammatory cytokines in the CSF of patients with Alz...

Taipa, Ricardo; das Neves, Sofia P.; Sousa, Ana L.; Fernandes, Joana; Pinto, Claudia; Correia, Ana P.; Santos, Ernestina; Pinto, Pedro S.

Cumulative data suggest that neuroinflammation plays a prominent role in Alzheimer's disease (AD) pathogenesis. The purpose of this work was to assess if patients with AD present a specific cerebrospinal fluid (CSF) cytokine profile and if it correlates to disease progression. We determined the levels of 27 cytokines in CSF of patients with AD and compared them with patients with frontotemporal dementia and non...


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