21 documents found, page 1 of 3
Extracorporeal Membrane Oxygenation in an Adolescent with Multisystem Inflammat...
Gago, C; Lorenzo, C; Pinto, S; R. Sousa, A; Camilo, C; Abecasis, FMultisystem inflammatory syndrome in children is a rare and potentially life-threatening disease that is associated with SARS-CoV-2 infection, character-ized by hyperinflammation and multiorgan involvement. Cardiovascular involvement is common, including myocardial dysfunction often leading to cardio-genic shock. We present the case of a 17-year-old boy with fever, odynophagia, maculopapular rash and abdominal ...
Hyperoside Supplementation in Preservation Media Surpasses Vitamin C Protection...
Moreira, MV; Pereira, SC; Guerra-Carvalho, B; Carrageta, DF; Pinto, S; Barros, A; Silva, BM; Oliveira, PF; Alves, MGBackground/Aims: Oxidative Stress (OS) is reported as one of the main causes of male infertility. Infertile couples often resort to assisted reproductive technology (ART) to achieve parenthood. However, preparation for ART protocols increases the exposer of gametes to OS. Thus, it is crucial to find suitable preservation media that can counteract the OS-induced damages in spermatozoa. In this work, we tested an...
Graphene oxide topical administration: Skin permeability studies
Silva, FALS; Costa-Almeida, R; Timochenco, L; Amaral, SI; Pinto, S; Gonçalves, IC; Fernandes, JR; Magalhães, FD; Sarmento, B; Pinto, AMNanostructured carriers have been widely used in pharmaceutical formulations for der-matological treatment. They offer targeted drug delivery, sustained release, improved biostability, and low toxicity, usually presenting advantages over conventional formulations. Due to its large surface area, small size and photothermal properties, graphene oxide (GO) has the potential to be used for such applications. Nanogr...
Chronic hepatitis C treatment in HIV co-infection in Portugal: Results from a c...
Miranda, AC; Mendez J, J; Serrão, R; Vale, F; Manata, MJ; Pinto, S; Gomes, A; Valente, C; Pacheco, P, et al.Direct-acting antiviral drugs (DAAs) have recently changed the paradigm of hepatitis C therapy, significantly improving treatment response rates, patient life expectancy and quality of life. In Portugal, sofosbuvir (SOF) and SOF/ledipasvir (SOF/LDV) were fully reimbursed by the National Health System since early 2015 and generalized use of interferon-free DAA based regimens became current practice. During 2016,...
Effect of high hydrostatic pressure extraction on biological activities and phe...
Moreira, SA; Silva, S; Costa, E; Pinto, S; Sarmento, B; Saraiva, JA; Pintado, MSatureja montana L. has several biological properties related to its diverse composition of secondary metabolites. Nevertheless, it has been mainly studied for its essential oil, with only a few studies on the profile and bioactivities of the bioactive compounds from its leaf extracts being reported. This work aimed to study the antioxidant activity (by oxygen radical absorbance capacity (ORAC) assay), antimicr...
Chronic Hepatitis C Treatment in HIV Co-Infection in Portugal: Results from a C...
Miranda, AC; Mendez, J; Serrão, R; Vale, F; Manata, MJ; Pinto, S; Gomes, A; Valente, C; Pacheco, P; Pazos, R; Pereira, R; Martins, A; Germano, IDirect-acting antiviral drugs (DAAs) have recently changed the paradigm of hepatitis C therapy, significantly improving treatment response rates, patient life expectancy and quality of life. In Portugal, sofosbuvir (SOF) and SOF/ledipasvir (SOF/LDV) were fully reimbursed by the National Health System since early 2015 and generalized use of interferon-free DAA based regimens became current practice. During 2016,...
Catarata pediátrica: a nossa experiência
Roque, J; Basto, R; Lopes, AS; Silva, D; Pinto, S; Pires, G; Prieto, I
Unilateral leukemic infiltration and acute angle closure as the first sign of B...
Silva, D; Mota, M; Bilé, A; Ramalho, M; Pinto, S; Pires, G; Teixeira, S; Prieto, IObjective: Unilateral ocular leukemic infiltration with acute angle closure is an infrequent complication of B-cell acute lymphoblastic leukemia (ALL-B). We present a clinical case of leukemic ocular infiltration as the sole manifestation of ALL-B relapse. Methods: Case description Results: A 15-year-old female with a history of acute lymphoblastic leukemia in remission for 2 years and pulmonary tuberculosis tr...
Changes in choroidal thickness following trabeculectomy and its correlation wit...
Silva, D; Lopes, AS; Henriques, S; Lisboa, M; Pinto, S; Vaz, F; Prieto, IPURPOSE: Evaluate whether there are significant changes in choroidal thickness following trabeculectomy, and how they relate do the decline in intraocular pressure. METHODS: This was a prospective evaluation of 28 eyes who underwent Moorfields modified trabeculectomy. The choroidal thickness was measured via OCT with enhanced depth imaging, before surgery and 1 day, 1 week and 1 month after surgery. Measurement...
Development of a sugar-free vehicle with universal characteristics for extempor...
Barbosa, C.M.; Pinto, S