Encontrados 26 documentos, a visualizar página 1 de 3
A portable and low-cost optical device for pigment-based taxonomic classificati...
Magalhães, Vitor; Pinto, Vânia Cristina Gonçalves; Sousa, Paulo Jorge Teixeira; Afonso, José A.; Gonçalves, L. M.; Fernández, Emilio; Minas, GraçaThe proliferation of certain phytoplankton species may lead to harmful algal blooms (HABs) that can affect living resources and human health. Therefore, an accurate identification of phytoplankton populations is essential for the sustainable management of some activities relevant for the blue economy, such as aquaculture, being also relevant for environmental monitoring and marine research purposes. Microalgae ...
Low-cost photoacoustic system for biomedical applications
Ferreira, João Filipe SObreiro; Pinto, Vânia Cristina Gonçalves; Matos, Tiago; Catarino, Susana Oliveira; Minas, Graça; Sousa, Paulo Jorge TeixeiraRecently, the field of photoacoustic (PA) imaging has garnered significant attention due to its ability to provide high-resolution images and real-time monitoring of biological tissues. However, PA systems have relied on expensive and complex laser sources and detection mechanisms, limiting their accessibility for widespread use in both clinical and research settings. So, this work aims to address these limitat...
Numerical and experimental analysis of mixing efficiency in passive micromixers...
Ferreira, Filipe Maurício Santos; Sousa, Paulo Jorge Teixeira; Minas, Graça; Lima, Rui Alberto Madeira Macedo; Pinto, Vânia Cristina GonçalvesPassive micromixers play a critical role in microfluidic applications, particularly in lab-on-a-chip devices, since they do not require external energy input, being simpler, cheaper and portable. This paper reports the mixing efficiency by numerical simulation (using COMSOL Multiphysics) and by experimental validation of two 2D polydimethylsiloxane micromixer geometries. The tested flow rate ratios, 1:1, 1:4 an...
Development of a photoacoustic acquisition system and their proof-of-concept fo...
Pinheiro, Bruna Regina Madureira; Pinto, Vânia Cristina Gonçalves; Dinis, Hugo Daniel Costa; Belsley, M.; Catarino, Susana Oliveira; Minas, GraçaRecently, Organ-on-a-Chip (OoC) platforms have arisen as an increasingly relevant experimental tool for successfully replicating human physiology and disease. However, there is a lack of a standard technology to monitor the OoC parameters, especially in a non-invasive and label-free way. Photoacoustic (PA) systems can be considered an alternative and accurate assessment method for OoC platforms. PA systems comb...
PDMS porous microneedles used as engineered tool in advanced microfluidic devic...
Maia, Renata Patrícia Faria; Sousa, Paulo Jorge Teixeira; Pinto, Vânia Cristina Gonçalves; Soares, Delfim; Lima, Rui Alberto Madeira MacedoThe advancement of organ-on-a-chip (OoC), as end-use preclinical tool, has been slackened with the techno logical and engineering challenges that in-situ real-time monitoring of physicochemical and biological param eters still represent. In this study, the envisioned solution to surpass this challenge is the integration of a microneedle (MN) patch into a microfluidic device to collect cell culture media directl...
Critical issues on the surface functionalization of plasmonic Au-Ag/TiO2 thin f...
Costa, Diogo; Pereira-Silva, Patrícia; Sousa, Paulo Jorge Teixeira; Pinto, Vânia Cristina Gonçalves; Borges, Joel; Vaz, Filipe; Minas, GraçaThis work reports on the surface functionalization of a nanomaterial supporting localized surface plasmon resonances (LSPRs) with (synthetic) thiolated oligonucleotide-based biorecognition elements, envisaging the development of selective LSPR-based DNA biosensors. The LSPR thin-film transducers are composed of noble metal nanoparticles (NPs) embedded in a TiO2 dielectric matrix, produced cost-effectively and s...
Portable and low-cost fluorometer for phytoplankton monitoring
Sá, Leonardo Rafael Correia; Pinto, Vânia Cristina Gonçalves; Sousa, Paulo Jorge Teixeira; Magalhães, Vitor H.; Carvalho, Denise Andreia MotaPhytoplankton monitoring using fluorescence spectroscopy techniques has been frequently used over time. This monitoring is based on the detection of the main photosynthetic pigment, chlorophyll-a, as its concentration is widely used as a proxy of phytoplankton biomass in the water column. However, the fluorometers available for their measurement and use in the field are still quite expensive and bulky, which li...
A microfluidic device for size-based microplastics and microalgae separation
Magalhães, Vitor H.; Pinto, Vânia Cristina Gonçalves; Sousa, Paulo Jorge Teixeira; Gonçalves, L. M.; Fernández, Emilio; Minas, GraçaPhytoplankton are microscopic marine algae that constitute the foundation of the aquatic food web. They are essential to drive life in the oceans but can also be harmful in the form of algae blooms, either by producing phytoplankton toxins or massive biomass proliferation. Microalgae cell size is a relevant morphologic trait that can help identifying species responsible for these blooms at early stages. Sorting...
Numerical simulation, fabrication, and characterization of a heating system for...
Ferreira, Gabriel Malheiro; Azevedo, Filipe M.; Sousa, Paulo Jorge Teixeira; Pinto, Vânia Cristina Gonçalves; Catarino, Susana OliveiraIn an organ-on-a-chip (OoC) device, temperature control is essential for a well-controlled and human representative microenvironment. This work presents the design, numerical simulation, fabrication and characterization of three aluminium microheater geometries for temperature control into an OoC device. Two of them are circular-based, with different curvature filleting angles and different line widths, and the...
Special issue on novel technology and applications of micro/nano devices and sy...
Pinto, Vânia Cristina Gonçalves; Sousa, Paulo Jorge Teixeira; Minas, Graça[Excerpt] The development of novel technologies and applications for micro/nano devices is an interdisciplinary subject that demands an integration of several research fields, such as material science, biotechnology, medicine, chemistry, informatics, optics, electronics, mechanics, and micro/nanotechnologies. In this regard, this Special Issue on “Novel Technology and Applications of Micro/Nano Devices and Syst...