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Caulerpin as a potential antiviral drug against herpes simplex virus type 1

Macedo,Nathália Regina Porto Vieira; Ribeiro,Michele S.; Villaça,Roberto C.; Ferreira,Wilton; Pinto,Ana Maria; Teixeira,Valéria L.; Cirne-Santos,Claudio

About 80% of the human adult population is infected with HSV-1. Although there are many anti-HSV-1 drugs available (acyclovir, ganciclovir, valaciclovir, foscarnet), their continuous use promotes the selection of resistant strains, mainly in ACV patients. In addition to resistance, the drugs also have toxicity, particularly when administration is prolonged. The study of new molecules isolated from green algae w...

Date: 2012   |   Origin: Oasisbr

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