2 documents found, page 1 of 1
Acute blockade of endogenous melatonin by Luzindole, with or without peripheral...
Matos,R.S.; Oriá,R.B.; Bruin,P.F.C.; Pinto,D.V.; Viana,A.F.S.C.; Santos,F.A.; Duarte,A.S.G.; Bruin,V.M.S.This study investigated the acute blockade of endogenous melatonin (MLT) using Luzindole with or without systemic lipopolysaccharide (LPS) challenge and evaluated changes in inflammatory and oxidative stress markers in the mouse jejunum. Luzindole is an MT1/MT2 MLT receptor antagonist. Both receptors occur in the small intestine. Swiss mice were treated with either saline (0.35 mg/kg, ip), Luzindole (0.35 mg/kg...
A Brazilian regional basic diet-induced chronic malnutrition drives liver infla...
Santos,M.J.S.; Canuto,K.M.; de Aquino,C.C.; Martins,C.S.; Brito,G.A.C.; Pessoa,T.M.R.P.; Bertolini,L.R.; de Sá Carneiro,I.; Pinto,D.V.Malnutrition is still considered endemic in many developing countries. Malnutrition-enteric infections may cause lasting deleterious effects on lipid metabolism, especially in children living in poor settings. The regional basic diet (RBD), produced to mimic the Brazilian northeastern dietary characteristics (rich in carbohydrate and low in protein) has been used in experimental malnutrition models, but few stu...