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Linear Peptide Analogues from Jatropha’s Orbitides Promote Migration of Human N...

Ramalho,Suelem D.; Pinto,Meri Emili F.; Andricopulo,Renata K.; Sanches,Paulo R. S.; Silveira,Edilberto R.; Cilli,Eduardo M.; Andricopulo,Adriano D.

Orbitides are a class of small naturally occurring cyclic peptides with structural and functional diversities. Their chemical properties make this class feasible to be obtained by solid phase peptide synthesis (SPPS). Therefore, this synthetic accessibility enables useful application and facilitates the identification of analogues, bioactivity studies, and thus, enables them to be applied to obtain peptide libr...

Date: 2019   |   Origin: Oasisbr

The Genus Psychotria: Phytochemistry, Chemotaxonomy, Ethnopharmacology and Biol...

Calixto,Nivea O.; Pinto,Meri Emili F.; Ramalho,Suelem D.; Burger,Marcela C. M.; Bobey,Antonio F.; Young,Maria Claudia Marx; Bolzani,Vanderlan S.

Psychotria genus (Rubiaceae) is featured into the angiosperm, being the most speciose genus comprising approximately 1600 species. The available references demonstrate that Psychotria has several uses on traditional medicine including spiritual and cultural purposes, and presents great potential on pharmacological properties, especially the one related to neurodegenerative diseases. Despite its wide biological ...

Date: 2016   |   Origin: Oasisbr

3',8"-biisokaempferide, a cytotoxic biflavonoid and other chemical constituents...

Pinto,Meri Emili F.; Silva,Marcelo Sobral da; Schindler,Elisabete; Barbosa Filho,José Maria; El-Bachá,Ramon dos Santos

A novel biflavonoid, named 3',8"-biisokaempferide (1), along with the known compounds amentoflavone (2), patagonic acid (3), (4aR,5S,6R,8aR)-5-[2-(2,5-Dihydro-5-methoxy-2-oxofuran-3-yl)ethyl]-3,4,4a,5,6,7,8,8a-octahydro-5,6,8a-trimethylnaphthalene-1-carboxylic acid (4), 5-caffeoylquinic acid methyl ester (5), 3,5-di-caffeoylquinic acid (6) and luteolin (7), were isolated of the leaves from Nanuza plicata. The c...

Date: 2010   |   Origin: Oasisbr

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