5 documents found, page 1 of 1
The History and Prospects of Rabbit Sperm Sexing
Pinto-Pinho, Patrícia; Ferreira, Ana F.; Pinto-Leite, Rosário; Fardilha, Margarida; Colaço, BrunoSperm sex selection is a longstanding challenge in the field of animal reproduction. The cuniculture industry, in particular producers of males or females for breeding purposes, would greatly benefit from the pre-selection of the offspring's sex. This review article overviews the current and future developments in rabbit sperm sexing technologies, as well as the implications of implementing these methodologies ...
Sustainable animal production: exploring the benefits of sperm sexing technolog...
Quelhas, Joana; Pinto-Pinho, Patrícia; Lopes, Graça; Rocha, António; Pinto-Leite, Rosário; Fardilha, Margarida; Colaço, BrunoThe sex of the animals is of paramount importance in many animal production systems. This is particularly evident in the production of milk or in breeding programs focused on the production of female animals. In some cases, slaughter or euthanasia of animals of the unwanted sex becomes the only solution, highlighting ethical and economic concerns. As global demand for food continues to rise, the importance of a...
Pregnancy Complications and Feto-Maternal Monitoring in Rabbits
Pinto-Pinho, Patrícia; Pinto, Maria de Lurdes; Monteiro, José; Fardilha, Margarida; Pinto-Leite, Rosário; Colaço, BrunoRabbit production holds significant relevance in modern agriculture due to its potential as a sustainable source of high-quality protein and efficient feed conversion, contributing to food security and economic diversification. Nevertheless, studies incorporating feto-maternal monitoring in this species are uncommon. This review gathers research on the monitoring and evaluation of factors affecting rabbit gesta...
Genetics of personalized medicine: cancer and rare diseases
Siefers Alves, Inês; Condinho, Manuel; Custódio, Sónia; Pereira, Bruna; Fernandes, Rafael; Gonçalves, Vânia; da Costa, Paulo J.; Lacerda, RafaelaThe 21st annual meeting of the Portuguese Society of Human Genetics (SPGH), organized by Luísa Romão, Ana Sousa and Rosário Pinto Leite, was held in Caparica, Portugal, from the 16th to the 18th of November 2017. Having entered an era in which personalized medicine is emerging as a paradigm for disease diagnosis, treatment and prevention, the program of this meeting intended to include lectures by leading natio...
In vivo and in vitro effects of RAD001 on bladder cancer
Vasconcelos-Nóbrega, Carmen; Pinto-Leite, Rosário; Arantes-Rodrigues, Regina; Ferreira, Rita; Brochado, Paulo; Cardoso, Maria L.; Palmeira, CarlosObjective: To evaluate the influence of Everolimus (RAD001) on chemically induced urothelial lesions in mice and its influence on in vitro human bladder cancer cell lines. Methods: ICR male mice were given N-butyl-N-(4-hydroxybutyl) nitrosamine in drinking water for a period of 12 weeks. Subsequently, RAD001 was administered via oral gavage, for 6 weeks. At the end of the experiment, all the animals were sacrif...