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Fecal Dipeptidyl Peptidase-4: An Emergent Biomarker in Inflammatory Bowel Disease

Pinto-Lopes, P; Melo, F; Afonso, J; Pinto-Lopes, R; Rocha, C; Melo, D; Macedo, G; Dias, CC; Carneiro, F; Magro, F

INTRODUCTION: Dipeptidyl peptidase-4 (DPP-4) is a membrane-bound glycoprotein that acts as a receptor but also exists in a soluble form. It has been recognized as a mediator of inflammation and considered a biomarker in inflammatory bowel disease (IBD). METHODS: We evaluated a prospectively recruited cohort, consisting of 101 patients with IBD, using validated clinical indexes; 22 patients with ulcerative colit...

Date: 2021   |   Origin: Repositório Aberto da Universidade do Porto
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