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HepatoPredict Accurately Selects Hepatocellular Carcinoma Patients for Liver Tr...

Andrade, Rita; Perez-Rojas, Judith; da Silva, Sílvia Gomes; Miskinyte, Migla; Quaresma, Margarida C; Frazão, Laura P; Peixoto, Carolina

Background/objectives: Hepatocellular carcinoma (HCC) is a major cause of cancer-related deaths rising worldwide. This is leading to an increased demand for liver transplantation (LT), the most effective treatment for HCC in its initial stages. However, current patient selection criteria are limited in predicting recurrence and raise ethical concerns about equitable access to care. This study aims to enhance pa...


Severe acute autoimmune hepatitis: how to early predict who will not respond to...

João, Mafalda; Carvalhana, Sofia; Moura, Miguel; Freitas, Luís Carlos; Silva, Andrea; Figueiredo, Pedro; Liberal, Rodrigo; Macedo, Guilherme

Backround: In acute severe autoimmune hepatitis (AS-AIH), the early identification of predictors of non-response to corticosteroids and the optimal timing for liver transplantation (LT) remains controversial. Aims: To determine early predictors of non-response to corticosteroids and to assess the usefulness of severity scores, namely the recently developed SURFASA. Methods: Retrospective multicentre cohort stud...


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