6 documents found, page 1 of 1
Multiple factors associated with forest decline in the context of control measu...
Pimentel, Carla S.; Pires, David; Campôa, João; Branco, Jordana; Marques, Raquel; Mota, Manuel M.; Calvão, TeresaWe thank Herdade da Aposti\u00E7a's administration for granting us access to their premises, and to two anonymous reviewers for suggestions that greatly improved a previous version of the manuscript. Publisher Copyright: © The Author(s) 2025.; Forest decline is a complex phenomenon; however, there is often a tendency to oversimplify by attributing it to a single cause, neglecting the interaction of multiple fac...
Polyphasic approach to the selection of Esteya isolates for the control of the ...
Pires, David; Vicente, Cláudia S.L.; Mota, Manuel; Inácio, Maria L.Funding Information: This work was supported by the Portuguese Foundation for Science and Technology (Funda\u00E7\u00E3o para a Ci\u00EAncia e a Tecnologia, FCT) and the European Social Fund, under the PhD fellowship 2021.08030.BD to DP, CEECIND/00040/2018 ( https://doi.org/10.54499/CEECIND/00040/2018/CP1560/CT0001 ) to CSLV, and the project UIDB/05183/2020 to MED ( https://doi.org/10.54499/UIDB/05183/2020 ; ht...
Insights into therapeutic liquid mixtures and formulations towards tuberculosis...
Santos, Filipa; Pires, David; Anes, Elsa; Duarte, Ana Rita C.Funding Information: This project has received funding from the European Union’s Horizon 2020 (European Research Council) under grant agreement No ERC-2016-CoG 725034 and was supported by the Associate Laboratory for Green Chemistry-LAQV. We also thank the support of ADEIM-FFUL (Associação para o Ensino e a Investigação em Microbiologia). Publisher Copyright: © 2023 The Author(s); Therapeutic liquid mixtures, a...
Linking Nematode Communities and Soil Health under Climate Change
Pires, David; Orlando, Valeria; Collett, Raymond L.; Moreira, David; Costa, Sofia R.; Inácio, Maria L.Funding Information: D.P. is supported by the Portuguese Foundation for Science and Technology (Fundação para a Ciência e a Tecnologia, FCT/MCTES), through grant 2021.08030.BD. At CBMA, this work was supported by the “Contrato-Programa” UIDB/04050/2020 funded by national funds through the FCT I.P. Publisher Copyright: © 2023 by the authors.; Soil health is intimately intertwined with ecosystem services. Climate...
Gold nanoparticles for vectorization of nucleic acids for cancer therapeutics
Ferreira, Daniela; Fontinha, David; Martins, Catarina; Pires, David; Fernandes, Alexandra R.; Baptista, Pedro V.Cancer remains a complex medical challenge and one of the leading causes of death worldwide. Nanomedicines have been proposed as innovative platforms to tackle these complex diseases, where the combination of several treatment strategies might enhance therapy success. Among these nanomedicines, nanoparticle mediated delivery of nucleic acids has been put forward as key instrument to modulate gene expression, be...
Ion channel blockers as antimicrobial agents, efflux inhibitors, and enhancers ...
Machado, Diana; Pires, David; Perdigão, João; Couto, Isabel; Portugal, Isabel; Martins, Marta; Amaral, Leonard; Anes, Elsa; Viveiros, MiguelGiven the ability of M. tuberculosis to survive as an intracellular pathogen and its propensity to develop resistance to the existing antituberculosis drugs, its treatment requires new approaches. Here the antimycobacterial properties of verapamil, thioridazine, chlorpromazine, flupenthixol and haloperidol were investigated against a panel of drug resistant M. tuberculosis strains, both in vitro and on human-in...