3 documents found, page 1 of 1
Antimicrobial activity and partial chemical structure of acylpolyamines isolate...
Barth,Tania; Silva,Aline; Santos,Simone Setubal dos; Santos,Jane Lima; Andrade,Patrícia Diniz; Tsai,Jessica; Caldas,Eloísa DutraAbstract Background: Acylpolyamines are one of the main non-peptide compounds present in spider venom and represent a promising alternative in the search for new molecules with antimicrobial action. Methods: The venom of Acanthoscurria natalensis spider was fractionated by reverse-phase liquid chromatography (RP-HPLC) and the antimicrobial activity of the fractions was tested using a liquid growth inhibition as...
Brazilian Theraphosidae: a toxicological point of view
Macedo,Keven Wender Rodrigues; Costa,Lucas Jeferson de Lima; Souza,Jéssica Oliveira de; Vasconcelos,Isadora Alves de; Castro,Jessica Schneider deAbstract The Theraphosidae family includes the largest number of species of the Mygalomorphae infraorder, with hundreds of species currently catalogued. However, there is a huge lack on physiologic and even ecologic information available, especially in Brazil, which is the most biodiverse country in the world. Over the years, spiders have been presented as a source of multiple biologically active compounds with...
Characterization of the first two toxins isolated from the venom of the ancient...
Oliveira,Natiela Beatriz de; Magalhães,Ana Carolina Martins; Bloch Jr.,Carlos; Beirão,Paulo Sérgio Lacerda; Silva,Anita de Oliveira; Melani,Rafael D.Abstract Background: Almost all Tityus characterized toxins are from subgenera Atreus and Tityus, there are only a few data about toxins produced by Archaeotityus, an ancient group in Tityus genus. Methods: Tityus (Archaeotityus) mattogrossensis crude venom was fractionated by high performance liquid chromatography, the major fractions were tested in a frog sciatic nerve single sucrose-gap technique. Two fracti...