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Maternal consumption of ultra-processed foods-rich diet and perinatal outcomes ...

Paula, Walkyria Oliveira; Patriota, Erika S. O.; Gonçalves, Vivian Siqueira Santos; Pizato, Nathalia Marcolini Pelucio

The consumption of ultra-processed food (UPF)-rich diets represents a potential threat to human health. Considering maternal diet adequacy during pregnancy is a major determinant for perinatal health outcomes, this study aimed to systematically review and meta-analyze studies investigating the association between maternal consumption of a UPF-rich diet and perinatal outcomes. Conducted according to the Preferre...

Date: 2022   |   Origin: Oasisbr

Effect of n-3 long-chain polyunsaturated fatty acid intake on the eicosanoid pr...

Schweitzer, Guilherme R. B.; Rios, Isabela N. M. S.; Gonçalves, Vivian Siqueira Santos; Magalhães, Kelly Grace; Pizato, Nathalia Marcolini Pelucio

Dietary n-3 polyunsaturated fatty acids (PUFAs) present beneficial effects on counteracting inflammation status, displaying a critical anti-inflammatory role and maintaining physiological homeostasis in obesity. The primary objective of this systematic review was to evaluate the effect of n-3 PUFAs intake on the eicosanoid profile of people with obesity and overweight. The search strategy on Embase, Scopus, Pub...

Date: 2021   |   Origin: Oasisbr

Potential neuroprotective and antiinfammatory efects provided by omega-3 (DHA) ...

Melo, Heloísa Antoniella Braz de; Nascimento, Gabriel Pasquarelli do; Corrêa, Rafael; Almeida, Raquel das Neves; Santos, Igor de Oliveira

Zika virus (ZIKV) has a strong tropism for the nervous system and has been related to post-infection neurological syndromes. Once neuronal cells are infected, the virus is capable of modulating cell metabolism, leading to neurotoxicity and cellular death. The negative efect of ZIKV in neuron cells has been characterized. However, the description of molecules capable of reversing these cytotoxic efects is still ...

Date: 2020   |   Origin: Oasisbr

Omega 3-DHA and delta-tocotrienol modulate lipid droplet biogenesis and lipopha...

Pizato, Nathalia Marcolini Pelucio; Kiffer, Larissa Fernanda Melo Vasconcelos; Luzete, Beatriz Christina; Assumpção, José Antonio Fagundes

Omega 3-docosahexaenoic acid (DHA) and vitamin E Delta-tocotrienol (Delta-T3) are extensively studied as protective nutrients against cancer development. Little is known about the biological mechanisms targeted by these bioactive molecules on lipid droplet (LD) biogenesis, an important breast cancer aggressiveness marker, and the occurrence of lipophagy in breast cancer cells. The aim of this study was to inves...

Date: 2019   |   Origin: Oasisbr

Omega-3 docosahexaenoic acid induces pyroptosis cell death in triple-negative b...

Pizato, Nathalia Marcolini Pelucio; Luzete, Beatriz Christina; Kiffer, Larissa Fernanda Melo Vasconcelos; Corrêa, Luís Henrique

The implication of inflammation in pathophysiology of several type of cancers has been under intense investigation. Omega-3 fatty acids can modulate inflammation and present anticancer effects, promoting cancer cell death. Pyroptosis is an inflammation related cell death and so far, the function of docosahexaenoic acid (DHA) in pyroptosis cell death has not been described. This study investigated the role of DH...

Date: 2019   |   Origin: Oasisbr

Efeito da dieta com diferentes proporçoes de ácidos graxos N-6 : N-3 sobre o cr...

Pizato, Nathalia Marcolini Pelucio

Orientador : Luiz Claudio Fernandes; Tese (doutorado) - Universidade Federal do Paraná, Setor de Ciencias Biológicas, Programa de Pós-Graduaçao em Biologia Celular e Molecular. Defesa: Curitiba, 2005; Inclui bibliografia; A nutrição é fator ambiental que sofreu alterações importantes durante os últimos dez mil anos. Achados arqueológicos e estudos sobre a evolução da dieta humana, a partir da era Paleolítica, s...

Date: 2018   |   Origin: Oasisbr

Diet quality assessment indexes

Carvalho, Kênia Mara Baiocchi de; Dutra, Eliane Said; Pizato, Nathalia Marcolini Pelucio; Gruezo, Nádia Dias; Ito, Marina Kiyomi

Various indices and scores based on admittedly healthy dietary patterns or food guides for the general population, or aiming at the prevention of diet-related diseases have been developed to assess diet quality. The four indices preferred by most studies are: the Diet Quality Index; the Healthy Eating Index; the Mediterranean Diet Score; and the Overall Nutritional Quality Index. Other instruments based on thes...

Date: 2017   |   Origin: Oasisbr

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