3 documents found, page 1 of 1
Exploring health professionals perceptions about drug related problems in older...
Roque, F.; Plácido, A. I.; Lima, F.; Herdeiro, M. T.Background/Introduction: The high prevalence of chronic diseases in the elderly population leads to a wide use of drugs by this population. Older patients use, on average, 2–5 prescription drugs daily, and about 20–40%, use more than 5 medicines. Besides the high level of prescription, elderly drugs overuse are also related to higher frequency and drug intake for longer durations than clinically indicated. Drug...
What think older patients about their medicines? (ISoP18-1430)
Roque, F.; Plácido, A. I.; Lima, F.; Herdeiro, M. T.Background/Introduction: Polypharmacy associated to the cognitive and physical functioning decline prone older patients to Drug-Related Problems. Drug-related problems are responsible for great percentage of hospitalizations and consequently increasing health care costs. Nevertheless, there are few studies exploring what older patients think about their medicines and how they are managing their medicines. Objec...
The role of endoplasmic reticulum in amyloid precursor protein processing and t...
Plácido, A. I.; Pereira, C. M. F.; Duarte, A. I.; Candeias, E.; Correia, S. C.; Santos, R. X.; Carvalho, C.; Cardoso, S.; Oliveira, C. R.The endoplasmic reticulum (ER) is the principal organelle responsible for the proper folding/processing of nascent proteins and perturbed ER function leads to a state known as ER stress. Mammalian cells try to overcome ER stress through a set of protein signaling pathways and transcription factors termed the unfolded protein response (UPR). However, under unresolvable ER stress conditions, the UPR is hyperactiv...