4 documents found, page 1 of 1
Current aspects of polycystic ovary syndrome: A literature review
ANDRADE,VICTOR HUGO LOPES DE; MATA,ANA MARIA OLIVEIRA FERREIRA DA; BORGES,RAFAEL SOARES; COSTA-SILVA,DANYLO RAFHAEL; MARTINS,LUANA MOTASUMMARY Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder with variable prevalence, affecting about one in every 15 women worldwide. The diagnosis of polycystic ovary syndrome requires at least two of the following criteria: oligoovulation and/or anovulation, clinical and/or biochemical evidence of hyperandrogenism and morphology of polycystic ovaries. Women with PCOS appear to have a highe...
Cytotoxic and toxicological effects of phthalimide derivatives on tumor and nor...
FERREIRA,PAULO MICHEL PINHEIRO; COSTA,PATRICIA MARÇAL DA; COSTA,ARINICE DE MENEZES; LIMA,DAISY JEREISSATI BARBOSA; DRUMOND,RENATA ROSADOEleven phthalimide derivatives were evaluated with regards to their antiproliferative activity on tumor and normal cells and possible toxic effects. Cytotoxic analyses were performed against murine tumors (Sarcoma 180 and B-16/F-10 cells) and peripheral blood mononuclear cells (PBMC) using MTT and Alamar Blue assays. Following, the investigation of cytotoxicity was executed by flow cytometry analysis and antitu...
Counteracting effects on free radicals and histological alterations induced by ...
ARAÚJO,ÉVERTON JOSÉ FERREIRA DE; OLIVEIRA,GUILHERME ANTÔNIO LOPES DE; SOUSA,LÍVIA QUEIROZ DE; BOLZANI,VANDERLAN DA SILVA; CAVALHEIRO,ALBERTO JOSÉABSTRACTCasearia sylvestris Swartz is a medicinal plant widely distributed in Brazil. It has anti-inflammatory, antiulcer and antitumor activities and is popularly used to treat snakebites, wounds, diarrhea, flu and chest colds. Its leaves are rich in oxygenated tricyclic cis-clerodane diterpenes, particulary casearins. Herein, we evaluated the antioxidant activities of a fraction with casearins (FC) isolated f...
Action of Aqueous Extracts of Phyllanthus niruri L. (Euphorbiaceae) leaves on M...
NEVES,ERASMOVLANE S.B.; FERREIRA,PAULO MICHEL PINHEIRO; LIMA,LEONARDO H.G.M.; PERON,ANA PAULAThis study aimed to evaluate the effects of aqueous extracts of dried Phyllanthus niruri L. (stonebreaker) leaves on Allium cepa L. root meristem cells at four concentrations, 0.02 (usual concentration), 0.04, 0.06 and 0.08mg/mL and exposure times of 24 and 48 hours. For each concentration we used a group of five onion bulbs that were first embedded in distilled water and then transferred to their respective co...