Immunoglubulin (Ig)M responses directed to oxida- tive specific epitopes (OSEs) and nitric oxide (NO)-adducts are significantly associated with major depression and physio- somatic symptoms. End of term serum IgM responses to OSEs and NO-adducts were assayed in pregnant women with ( n =24) and without prenatal depression ( n = 25) as well as in 24 non- pregnant women. Associations of IgM/IgA responses to Gram- ...
Objectives: To examine oxidative & nitrosative stress (O & NS) biomarkers at the end of term in relation to perinatal affective symptoms, neuro-immune biomarkers and pregnancy-related outcome variables. Methods: We measured plasma advanced oxidation protein products (AOPP), nitric oxide metabolites (NOx), total radical trapping antioxidant parameter (TRAP), -sulfhydryl (-SH), peroxides (LOOH) and paraoxonase (P...