59 documents found, page 1 of 6

Screening of plants found in the State of Amazonas, Brazil for activity against...

Made available in DSpace on 2021-07-14T10:41:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2004. Added 1 bitstream(s) on 2021-07-14T11:36:07Z : No. of bitstreams: 1 S0044-59672004000100012.pdf: 277183 bytes, checksum: 7e7a8289dcd98d1df6c2879e5159ad69 (MD5); Extratos aquosos, etanólicos e metanólicos, representando principalmente espécies vegetais nativas encontradas na região Amazônica, foram preparados,...

Chemical constituents from stems of simaba guianensis subesp. ecaudata (cronquist)

Simaba guianensis subesp. ecaudata (Simaroubaceae) is a tree found in the Brazilian Amazon. This work describes for the first time the fractionation of stems of this species that resulted in the isolation of the cytotoxic triterpene piscidinol A, the alkaloid 9-methoxycanthin-6-one, caryophyllene oxide, also isolated for the first time from this species and a new alkaloid (6-methoxy-(9H-β-carbolin-1-il)-(Z)-2-p...

Involvement of intrinsic mitochondrial pathway in neosergeolide-induced apoptos...

Context: Quassinoids are biologically active secondary metabolites found exclusively in the Simaroubaceae family of plants. These compounds generally present important biological properties, including cytotoxic and antitumor properties. Objective: In the present study, the cytotoxic effects of neosergeolide, a quassinoid isolated from Picrolemma sprucei Hook. f., were evaluated in human promyelocytic leukemia c...

Indolealkalaloids from the bark of Aspidosperma vargasii and A. desmanthum

Fractionation of extracts resulted in isolation and identification of indole alkaloids ellipticine and N-methylteti:ahydroellipticine from. A. vargasii and aspidocarpine from A. desmanthum. Identification of these compounds was achieved based on IR, MS, 1H, 13C and 2-D NMR data and comparison to data in the literature.

Erratum to: Antioxidant activity and peroxidase inhibition of Amazonian plants ...

Gram-scale isolation of isobrucein B and neosergeolide from Picrolemma sprucei ...

Os quassinóides neosergeolida e isobruceína B, obtidos de Picrolemma sprucei, possuem atividades antitumoral, antimalárica, anti-helmíntica, citotóxica, inseticida e anti-leishmania comprovadas em estudos in vitro. Há interesse no estudo farmacológico in vivo dessas substâncias naturais e de seus derivados semi-sintéticos, porém a quantidade obtida nos processos de extração tem se mostrado um fator limitante à ...

Antioxidant, cytotoxic and UVB-absorbing activity of Maytenus guyanensis Klotzc...

Maytenus guyanensisKlotzch. é uma árvore medicinal proveniente da Amazônia conhecida comochichuá (xixuá)e no Peru e Colombia porchuchuhuasi. É utilizada medicinalmente como estimulante, tônico e relaxante muscular, para o alívio de artrite, reumatismo, hemorróidas, rim inchado, erupções de pele, prevenção do câncer de pele, entre outros. Vários solventes e métodos de extração foram aplicados a cascas secas pulv...

Plant extracts, isolated phytochemicals, and plant-derived agents which are let...

The recent scientific literature on plant-derived agents with potential or effective use in the control of the arthropod vectors of human tropical diseases is reviewed. Arthropod-borne tropical diseases include: amebiasis, Chagas disease (American trypanosomiasis), cholera, cryptosporidiosis, dengue (hemorrhagic fever), epidemic typhus (Brill-Zinsser disease), filariasis (elephantiasis), giardia (giardiasis), h...

Screening and antifungal activity of a β-carboline derivative against cryptococ...

Background. Cryptococcosis is a fungal disease of bad prognosis due to its pathogenicity and the toxicity of the drugs used for its treatment. The aim of this study was to investigate the medicinal potential of carbazole and β-carboline alkaloids and derivatives against Cryptococcus neoformans and C. gattii. Methods. MICs were established in accordance with the recommendations of the Clinical and Laboratory Sta...

Screening Of Plants Found In The State Of Amazonas, Brazil For Larvicidal Activ...