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Drug repurposing opportunities in pancreatic ductal adenocarcinoma

Rebelo, R; Polónia, B; Santos, LL; Vasconcelos, MH; Xavier, CPR

Pancreatic ductal adenocarcinoma (PDAC) is considered one of the deadliest tumors worldwide. The diagnosis is often possible only in the latter stages of the disease, with patients already presenting an advanced or metastatic tumor. It is also one of the cancers with poorest prognosis, presenting a five-year survival rate of around 5%. Treatment of PDAC is still a major challenge, with cytotoxic chemotherapy re...

Date: 2021   |   Origin: Repositório Aberto da Universidade do Porto
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