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ANALYSIS OF 16528 INDIVIDUAL 24-HOUR AMBULATORY BLOOD PRESSURE MONITORING RECOR...
Azevedo, Isabel; Barbosa, Loide; Silva, José Alberto; Polónia, JorgeTwenty-four hour ambulatory blood pressure (ABPM) is an essential tool in the evaluation of hypertensive patients. The present study consisted of the retrospective evaluation of 16528 ABPM records made at the Hypertension and Cardiovascular Risk Unit of ULS Matosinhos between January 2000 and December 2022 in patients with arterial hypertension, under medication and without previous cardiovascular events. This ...
"What do we think?": a qualitative exploratory study of acceptability and exper...
Lopes, Susana; Diniz, Filipa; Mesquita Bastos, José; Oliveira, José; Polónia, Jorge; Alves, Alberto Jorge; Ribeiro, Fernando; Figueiredo, DanielaPurpose: Aerobic exercise training programs decrease blood pressure in individuals with resistant hypertension. However, participants' experiences regarding exercise training participation are unknown and often undervalued. Therefore, participant's experiences and program acceptability of the exercise arm of the EnRicH trial, a randomized clinical trial investigating the effect of a 12-week aerobic exercise tra...
Can exercise training reduce central systolic blood pressure among patients wit...
Lopes, Susana; Mesquita-Bastos, José; Leitão, Cátia; Ribau, Veronica; Garcia, Catarina; Oliveira, José; Polónia, Jorge; Alves, AlbertoIntroduction: Resistant hypertension is a problematic phenotype marked by the limited efficacy of available blood pressure-lowering treatments [1], such as antihypertensive medicines and kidney denervation [2-4]. Given its economic and health-related impact, it is a major medical and societal concern. Patients with resistant hypertension have a higher risk of myocardial infarction, stroke, heart failure, chroni...
Avaliação da Problemática da Doença Renal Crónica (Não Diálise) em Portugal: Ab...
Ferreira, Aníbal; Raposo, João; Rocha, João; Polónia, Jorge; Cabrita, José; Jacinto, Nuno; Branco, Patrícia; Birne, Rita; Maia, Margarida; Marcelo, AnaChronic kidney disease is a global public health problem and is associated with an increased risk of serious cardiovascular events and mortality. Since Portugal is one of the European countries with the highest incidence of this pathology, we emphasize the importance of promoting the increase of notoriety of this problem with the health authorities, the health professionals and the scientific community. We pres...
Pharmacovigilance of COVID-19 Vaccines in Pregnant and Lactating Women
Silva, Ana Marta; Ribeiro-Vaz, Inês; Ferreira-da-Silva, Renato; Cruz-Correia, Ricardo; Polónia, Jorge; Bernardes, JoãoN/a.; N/a.
Efeito da empagliflozina para além do controlo glicémico: benefício cardiovascu...
Monteiro, Pedro; Aguiar, Carlos; Matos, Pedro; Silva‐Nunes, José; Birne, Rita; Branco, Patrícia; Calado, Joaquim; Melo, Miguel; Polónia, JorgeA prevalência da diabetes mellitus tipo 2 (DMT2) continua a aumentar e a sua associação com a doença cardiovascular (CV) tem levado à incorporação e valorização de endpoints CV nos ensaios clínicos sobre o tratamento da DMT2. Este artigo faz uma revisão dos vários ensaios já realizados e em desenvolvimento, neste âmbito, com especial enfoque no estudo EMPA‐REG OUTCOME. Neste estudo, a empagliflozina, um inibido...
The Chester step test is a valid tool to assess cardiorespiratory fitness in ad...
Izquierdo, Mireia Cano; Lopes, Susana; Teixeira, Manuel; Polónia, Jorge; Alves, Alberto Jorge; Mesquita-Bastos, José; Ribeiro, Fernando
POPs’ effect on cardiometabolic and inflammatory profile in a sample of women w...
Ferro, Ana; Teixeira, Diana; Pestana, Diogo; Monteiro, Rosário; Santos, Cristina C.; Domingues, Valentina F.; Polónia, Jorge; Calhau, ConceiçãoPersistent organic pollutants (POPs) are man-made compounds with metabolic disruption impact. We investigated the effect of POP exposure in the cardiometabolic and inflammatory profile in a population of women with obesity and hypertension. In 43 premenopausal women (22 treated vs. 21 nontreated) undergoing bariatric surgery, blood and adipose tissue samples (visceral (vAT) and abdominal subcutaneous (scAT)) we...
Empagliflozina e a nova era no tratamento da diabetes tipo 2: para além do cont...
Silva-Nunes, José; Aguiar, Carlos; Birne, Rita; Branco, Patrícia; Calado, Joaquim; Matos, Pedro; Melo, Miguel; Monteiro, Pedro; Polónia, JorgeA diabetes mellitus tipo 2 (DMT2) tem associado um risco aumentado de mortalidade, principalmente, por doença cardiovascular (DCV). Interessa ter disponíveis opções terapêuticas que permitam o controlo glicémico mas que considerem, igualmente, a atuação sobre fatores de risco cardiovascular e a redução de eventos micro e macrovasculares. Nos últimos anos foram desenvolvidos vários inibidores do transporte renal...
Diabetes Mellitus in Portugal: Relevance of Suitable Pharmacological Therapy
Brito de Sá, Armando; Oliveira, Catarina; Carvalho, Davide; Raposo, João; Polónia, Jorge; Aranda da Silva, José; Medina, José LuísDiabetes is a major public health problem in Portugal, with a estimated prevalence of 13,1% in the population aged between 20 and 79 years old, which corresponds to more than 1 million individuals who suffer from this disease. Diabetes has an overwhelmingly high social, economic and human cost. Indeed, costs associated with diabetes represent in Portugal approximately 10% of the total expenditure in Health and ...