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Clostridioides difficile Toxin A-Induced Wnt/β-Catenin Pathway Inhibition Is Me...

Martins, Conceição S.; Costa, Deiziane V. S.; Lima, Bruno B.; Leitäo, Renata Ferreira de Carvalho; Freire, Gildênio E.; Silva, Guilherme F. M.

Clostridioides difficile toxin A (TcdA) has been shown to inhibit cellular Wnt signaling, the major driving force behind the proliferation of epithelial cells in colonic crypts, likely through the inhibition of β-catenin nuclear translocation. Herein, we aimed to advance the understanding of this mechanism by replicating the findings in vivo and by investigating the specific role of Rac1, a member of the Rho GT...

Data: 2021   |   Origem: Oasisbr

Letter on statuary and power. Statues as political statements

Abreu, José G.

Statuary, statue and statute all derive from the Latin verb statuere, meaning “to cause, to stand, to set up”, whose root comes from the nom status, meaning “standing, position”. However, if we decide to look for even older origins, we will find out that all these words derive from the Proto-Indo-European root stā-, meaning “to stand, set down, make or be firm".


Insights for the endorsement of a holistic approach for public sculpture research

Moreira, Patricia; Vieira, Eduarda; Abreu, José G.

This article reflects on the holistic approach for public sculpture research within the BIONANOSCULP project, focusing on the reasons behind the project development, its objectives, selected achievements and future outcomes. Focusing on one of the seven selected sculptures that were studied within the project, “Afonso de Albuquerque”, the reasons behind the selection of these public art works, their historical ...


Editorial

Abreu, José G.

Since 20th century’s last decades, public art, and its youngest expression, street art, have been obtaining increasing impact on non-specialized audiences, and gaining greater attention by critics and other specialists, for public art is the artistic discipline “that characterizes best the manifestations of the last third of the 20th century” (Maderuelo, 2000:240). Nowadays, there is no urban improvement, no ar...


Letter on statuary and power. Statues as political statements

Abreu, José G.

Statuary, statue and statute all derive from the Latin verb statuere, meaning “to cause, to stand, to set up”, whose root comes from the nom status, meaning “standing, position”. However, if we decide to look for even older origins, we will find out that all these words derive from the Proto-Indo-European root stā-, meaning “to stand, set down, make or be firm".


Insights for the endorsement of a holistic approach for public sculpture research

Moreira, Patricia; Vieira, Eduarda; Abreu, José G.

This article reflects on the holistic approach for public sculpture research within the BIONANOSCULP project, focusing on the reasons behind the project development, its objectives, selected achievements and future outcomes. Focusing on one of the seven selected sculptures that were studied within the project, “Afonso de Albuquerque”, the reasons behind the selection of these public art works, their historical ...


Editorial

Abreu, José G.

Since 20th century’s last decades, public art, and its youngest expression, street art, have been obtaining increasing impact on non-specialized audiences, and gaining greater attention by critics and other specialists, for public art is the artistic discipline “that characterizes best the manifestations of the last third of the 20th century” (Maderuelo, 2000:240). Nowadays, there is no urban improvement, no ar...


Letter on statuary and power: statues as political statements

Abreu, José G.

Statuary, statue and statute all derive from the Latin verb statuere, meaning “to cause, to stand, to set up”, whose root comes from the nom status, meaning “standing, position”. However, if we decide to look for even older origins, we will find out that all these words derive from the Proto-Indo-European root stā-, meaning “to stand, set down, make or be firm".


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