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Erratum to
Miranda, Hugo Vicente; Szegő, Éva M.; Oliveira, Luís M.A.; Breda, Carlo; Darendelioglu, Ekrem; de Oliveira, Rita M.; Ferreira, Diana G.
Data: 2021
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Origem: Repositório Institucional da UNL
Glycation potentiates neurodegeneration in models of Huntington's disease
Miranda, Hugo Vicente; Gomes, Marcos Antonio; Branco-Santos, Joana; Breda, Carlo; Lazaro, Diana F; Lopes, Lusa Vaqueiro; Herrera, FedericoProtein glycation is an age-dependent posttranslational modification associated with several neurodegenerative disorders, including Alzheimer's and Parkinson's diseases. By modifying aminogroups, glycation interferes with folding of proteins, increasing their aggregation potential. Here, we studied the effect of pharmacological and genetic manipulation of glycation on huntingtin (HTT), the causative protein in ...
Data: 2016
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Origem: Repositório Institucional da UNL
Erratum to
Klionsky, Daniel J.; Abdelmohsen, Kotb; Abe, Akihisa; Abedin, Md Joynal; Abeliovich, Hagai; Arozena, Abraham Acevedo; Adachi, Hiroaki
Data: 2016
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Origem: Repositório Institucional da UNL