12 documents found, page 1 of 2
Dynamics of blaOXA-23 gene transmission in Acinetobacter spp. from contaminated...
Silva, Joana; Menezes, Juliana; Fernandes, Laura; Marques, Cláudia; Costa, Sofia; Timofte, D.; Amaral, Andreia; Pomba, C.Background Carbapenem-resistant Acinetobacter baumannii is a common pathogen associated with healthcare-acquired infections, and robust infection prevention and control protocols exist in human healthcare settings. In contrast, infection prevention and control (IPC) standards are limited in veterinary medicine, necessitating further investigation. Aim Examine the possible transmission of carbapenem-resistant Ac...
Molecular epidemiology of Clostridioides difficile in companion animals: Geneti...
Alves, Frederico; Castro, Rita; Pinto, Miguel; Nunes, Alexandra; Pomba, C.; Oliveira, Manuela; Silveira, Leonor; Gomes, Joao Paulo; Oleastro, MonicaIntroduction: The changing epidemiology of Clostridioides difficile reflects a well-established and intricate community transmission network. With rising numbers of reported community-acquired infections, recent studies tried to identify the role played by non-human reservoirs in the pathogen's transmission chain. This study aimed at describing the C. difficile strains circulating in canine and feline populatio...
Companion animals-An overlooked and misdiagnosed reservoir of carbapenem resist...
da Silva, Joana Moreira; Menezes, Juliana; Marques, Cátia Filipa Saraiva; Pomba, C.ABSTRACT - The dissemination of antimicrobial-resistance is a major global threat affecting both human and animal health. Carbapenems are human use β-lactams of last resort; thus. the dissemination of carbapenemase-producing (CP) bacteria creates severe limitations for the treatment of multidrugresistant bacteria in hospitalized patients. Even though carbapenems are not routinely used in veterinary medicine, re...
Human and companion animal proteus mirabilis sharing
Marques, Cátia Filipa Saraiva; Belas, Adriana; Menezes, Juliana; da Silva, Joana Moreira; Cavaco-Silva, Patrícia; Trigueiro, Graça; Gama, LuisProteus mirabilis is an important pathogen that is associated with urinary tract infections. This study aims to determine the colonization and sharing of P. mirabilis between healthy companion animals and humans that are living together and to evaluate the clonal relatedness of the fecal and clinical stains. Eighteen households (24 humans, 18 dogs, 8 cats) with at least one human–animal pair were studied. Fecal...
Virulence potential of biofilm-producing Staphylococcus pseudintermedius, Staph...
Andrade, Mariana; Oliveira, Ketlyn; Morais, Catarina; Abrantes, Patrícia; Pomba, C.; Rosato, Adriana E.; Couto, Isabel; Costa, Sofia SantosABSTRACT . Coagulase-positive staphylococci (CoPS) account for most bacteria-related pyoderma in companion animals. Emergence of methicillin-resistant strains of Staphylococcus pseudintermedius (MRSP), Staphylococcus aureus (MRSA) or Staphylococcus coagulans (MRSC), often with multidrugresistant (MDR) phenotypes, is a public health concern. The study collection comprised 237 staphylococci (S. pseudintermedius (...
Staphylococcus aureus causing skin and soft tissue infections in companion anim...
Costa, Sofia Santos; Rute, Ribeiro; Serrano, Maria; Oliveira, Ketlyn; Ferreira, Carolina; Leal, Marta; Pomba, C.; Couto, IsabelABSTRACT - Staphylococcus aureus is a relevant agent of skin and soft tissue infections (SSTIs) in animals. Fifty-five S. aureus comprising all SSTI-related isolates in companion animals, collected between 1999 and 2018 (Lab 1) or 2017 and 2018 (Lab 2), were characterized regarding susceptibility to antibiotics and heavy metals and carriage of antimicrobial resistance determinants. Clonal lineages were establis...
Proposal of epidemiological cutoff values for Apramycin 15 μg and Florfenicol 3...
Costa, Sofia Santos; Ferreira, Carolina; Ribeiro, Rute; Fessler, Andrea T.; Schink, Anne-Kathrin; Kadlec, Kristina; Kaspar, Heike; Amaro, AnaApramycin and florfenicol are two antimicrobial agents exclusively used in veterinary medicine. Resistance determinants to these antimicrobial agents have been described in several staphylococci, yet no inhibition zone-based epidemiological cutoff (ECOFF) values are available to detect populations harboring resistance mechanisms. In this study, we propose disk diffusion inhibition zone ECOFF values of Staphyloc...
Oxa-181-producing extraintestinal pathogenic escherichia coli sequence type 410...
Brilhante, Michael; Menzes, Juliana; Belas, Adriana; Feudi, Claudia; Schwarz, Stefan; Pomba, C.; Perretena, VincentTwo multidrug-resistant and carbapenemase-producing Escherichia coli clones of sequence type 410 were isolated from fecal samples of a dog with skin infection on admission to an animal hospital in Portugal and 1 month after discharge. Whole-genome sequencing revealed a 126,409-bp Col156/IncFIA/IncFII multidrug resistance plasmid and a 51,479-bp IncX3 blaOXA-181-containing plasmid. The chromosome and plasmids ca...
Streptococcus canis are a single population infecting multiple animal hosts des...
Pinho, MD; Foster, G; Pomba, C.; Machado, MP; Baily, JL; Kuiken, T; Melo-Cristino, J; Ramirez, M; Vaz, T; Giao, MABSTRACT - Streptococcus canis is an animal pathogen which occasionally causes infections in humans. The S. canis M-like protein (SCM) encoded by the scm gene, is its best characterized virulence factor but previous studies suggested it could be absent in a substantial fraction of isolates. We studied the distribution and variability of the scm gene in 188 S. canis isolates recovered from companion animals (n =...
Evidence of sharing of Klebsiella pneumoniae strains between healthy companion ...
Marques, Cátia Filipa Saraiva; Belas, Adriana; Aboim, Catarina; Cavaco-Silva, Patrícia; Trigueiro, Graça; Gama, Luis; Pomba, C.This study aimed to characterize the fecal colonization and sharing of Klebsiella pneumoniae strains between companion animals and humans living in close contact. Fecal samples were collected from 50 healthy participants (24 humans, 18 dogs, and 8 cats) belonging to 18 households. Samples were plated onto MacConkey agar (MCK) plates with and without cefotaxime or meropenem supplementation. Up to five K. pneumon...