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In vitro initial immune response against Leishmania amazonensis infection is ch...

Coêlho, Zirlane Castelo B; Teixeira, Maria Jania; Mota, Erika Freitas; Frutuoso, Mércia Sindeaux; Silva, João Santana da; Barral, Aldina

The initial encounter of Leishmania with its host’s immune system is important in the outcome of infection. Previous studies have shown that PBMCs from healthy volunteers (HV) exposed to Leishmania differ in IFN-γ production. We have expanded such observations evaluating the profi le and kinetics of cytokines (IFN-γ, IL-12p70, IL-10, IL-13), chemokines (CCL5, CCL3, CCL4, CXCL10), and chemokine receptors (CCR1,C...

Date: 2021   |   Origin: Oasisbr

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