27 documents found, page 1 of 3

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Descentralização do acesso a medicamentos do Componente Especializado da Assist...

Rossignoli, P; Pontarolli, D; Limberger, PM; Pontarolo, R; Fernandez-Llimos, F

<jats:p>O Componente Especializado da Assistência Farmacêutica contempla medicamentos para tratamento de doenças crônicas, incluindo doenças raras, no âmbito do Sistema Único de Saúde. As secretarias estaduais de saúde são responsáveis pelo acesso a esses medicamentos. No Paraná, originalmente os locais de acesso se limitavam aos 22 municípios-sede de regionais de saúde. O objetivo deste estudo foi descrever a ...


Variabilidade nos preços de aquisição pública de medicamentos do grupo 1A do co...

Rossignoli, P; Pontarolo, R; Fernandez-Llimos, F

<jats:p>Resumo Objetivo Avaliar a diferença nos preços de aquisição de medicamentos do grupo 1A do Componente Especializado da Assistência Farmacêutica entre as compras realizadas pelo Ministério da Saúde e as realizadas pela Secretaria de Estado da Saúde do Paraná. Métodos Tratou-se de estudo observacional retrospectivo comparando preços de medicamentos adquiridos centralizadamente pelo Ministério da Saúde e a...


Variability in public procurement prices for Group 1A drugs in the specialized ...

Rossignoli, P; Pontarolo, R; Fernandez-Llimos, F

Objective: To assess the difference in acquisition prices of Group 1A drugs in the Specialized Pharmaceutical Component between purchases made by the Brazilian Ministry of Health and those made by the Paran & aacute; State Health Department. Methods: This was a retrospective observational study comparing prices of medications acquired centrally by the Brazilian Ministry of Health and those acquired by the State...


Methodological quality and clinical recommendations of guidelines on the manage...

Deffert, F; Vilela, APO; Cobre, AD; Furlan, LHP; Tonin, FS; Fernandez-Lllimos, F; Pontarolo, R

Background Clinical practice guidelines (CPGs) are statements to assist practitioners and stakeholders in decisions about healthcare. Low methodological quality guidelines may prejudice decision-making and negatively affect clinical outcomes in non-communicable diseases, such as cardiovascular diseases worsted by poor lipid management. We appraised the quality of CPGs on dyslipidemia management and synthesized ...


Variability in Drug Procurement within Group 1B of the Pharmaceutical Specializ...

Rossignoli, P; Pontarolo, R; Fernandez Llimos, F

In the Brazilian Health System (SUS), drugs covered by the Specialized Pharmaceuti-cal Scheme (CEAF) receive federal funding and can be procured either centrally (Group 1A) or by individual states (Federal Units -UF) (Group 1B). Unlike other countries where national pro-curement prices are negotiated centrally by the government, public procurement in Brazil follows a public auction procedure, potentially result...


Socioeconomic factors influencing access to drugs from the Specialized Componen...

Limberger, PM; Rossignoli, P; Rotta, I; Lazo, REL; Domingues, KZA; Fernandez-Llimos, F; Pontarolo, R

The Specialized Component of Pharmaceutical Services (CEAF) is a crucial strategy for accessing medicines through the Brazilian Public Health System, holding the highest budgetary impact on outpatient pharmaceutical care. This study aimed to assess the association of socioeconomic factors with access to CEAF drugs in municipalities throughout Paran & aacute; from 2010 to 2019. It utilized a retrospective, obser...


Methodological quality and risk of bias of meta-analyses of pharmacy services: ...

Bonetti, AF; Tonin, FS; Della Rocca, AM; Lucchetta, RC; Fernandez Llimos, F; Pontarolo, R

Background: A suboptimal meta-analysis with misleading conclusions, frequently published in the healthcare journals, can compromise decision making in clinical practice. Objective: To evaluate the reporting quality, methodological quality, and risk of bias of meta-analyses of pharmacy services. Methods: Systematic searches to identify all the meta-analyses reporting the effect of pharmacy services were performe...


Systematic review with network meta-analysis on the treatments for latent tuber...

Santos, JM; Fachi, MM; Beraldi-Magalhaes, F; Boger, B; Junker, AM; Domingos, EL; Imazu, P; Fernandez-Llimos, F; Tonin, FS; Pontarolo, R

Background: We aimed to synthesize the evidence on the efficacy and safety of different treatment regimens for latent tuberculosis infection (LTBI) in children and adolescents. Methods: A systematic review with network meta-analysis was performed (CRD142933). Searches were con-ducted in Pubmed and Scopus (Nov-2021). Randomized controlled trials comparing treatments for LTBI (patients up to 15 years), and report...


Mapping community pharmacy services in Brazil: a scoping review

Garabeli, AA; Benetoli, A; Halila, GC; Machinski, I; Tonin, FS; Fernandez-Llimos, F; Pontarolo, R

The delivery of clinical pharmacy services has been growing in Brazilian community pharmacies, and it is necessary to have a comprehensive understanding of the topic. This scoping review aimed to provide an overview of Brazilian studies about clinical pharmacy services in community pharmacies. Original research articles, with no restriction of time, study design, or patient's health condition, were included. Se...


Pharmacovigilance: an evaluation on the practice of pharmacists acting in pharm...

Fedalto, MB; Tonin, FS; Borba, HHL; Ferreira, VL; Correr, CJ; Fernandez-Llimos, F; Pontarolo, R

Pharmacists acting in pharmacies and drugstores stores are some of the most accessible healthcare providers and the last to intervene before the patient takes their medicine. This puts the pharmacist in a position of authority that should be harnessed for the benefit of health. Thus, this professional is strategic for performing pharmacovigilance. Our objective of this study was to interrogate the practice of p...


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