Trastuzumab Deruxtecan is indicated for the treatment of Human Epidermal growth factor Receptor-type 2 HER2-positive or HER2-low breast cancer, showing favorable efficacy and safety profiles. However, it can lead to some severe adverse events, such as interstitial lung disease. We performed four regional experience sharing sessions and one final national discussion session, with the participation of several nur...
A cancer diagnosis may bring multiple symptoms amenable to deeply affect quality of life (QoL). Systematic monitoring of patient-reported outcomes (PRO’s) allows to evaluate symptoms, to understand the patient’s perception about the impact of the disease and its treatments and to evaluate the effectiveness of implemented interventions. All these are essential steps to ensure that quality care adapted to patient...
Introduction: Myeloproliferative neoplasms (MPN), including polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF), significantly impact patients’ quality of life (QoL). The symptom burden assessment and continuous monitoring using the MPN Symptom Assessment Form Total Symptom Score (MPN-10) allows detecting symptomatic changes that may be signs of disease progression and can be used as ...
The administration of antineoplastic drugs can generate immediately hypersensitivity reactions, in Oncology-Day Care Unit hospitals. The incidence and severity are difficult to predict and the signs and symptoms vary, ranging from erythematous skin reactions to severe anaphylactic reactions, with a lethal risk. Prevention is essential to reduce the prevalence and severity of these events and earl...
From the diagnosis of needs in this group of patients, with the work of a large group of experts in the area, an intervention model called U-Care was created. This model defines a program that aims to satisfy individual needs, from a multidimensional perspective (physical, psychosocial and spiritual), in the course of the disease, even when treatment alternatives are exhausted and the focus becomes exclusively ...
Myeloproliferative Neoplasms Philadelphia Negative Chromosome (NPM Ph¯) are a group of chronic hematological diseases of course and heterogeneous evolution, treated with oral therapy and with great impact on patients’ quality of life. International guidelines recommend that patients undergoing new, complex and long-term oral treatment drugs be followed up by multidisciplinary teams that promote patient and fami...
A partir do diagnóstico de necessidades neste grupo de doentes, com o trabalho de um grupo alargado de especialistas na área, criou-se um modelo de intervenção, chamado U-Care. Este modelo define um programa que pretende satisfazer necessidades individuais, numa perspetiva multidimensional (física, psicossocial e espiritual), no decurso da doença, mesmo quando se esgotam as alternativas de tratamento e o foco p...
The subcutaneous formulations of Trastuzumab (Herceptin®) and Rituximab (MabThera®) are more comfortable for the people affected by cancer who need this type of treatment and are also easier to prescribe, prepare and administer. This type of formulations demands nurses to update their knowledge, so that good practices are assured in the health care setting. With the purpose to support nurses in this matter, the...