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Lucius phenomenon: the importance of a primary dermatological care
Pinheiro,Juliana Viana; Pontes,Maria Araci de Andrade; Medeiros Neto,José Urbano de; Gonçalves,Heitor de SáAbstract Leprosy presents a varied clinical spectrum. Lucius phenomenon is a rare leprosy reaction characterized by erythematous, painful, slightly infiltrated macules and hemorrhagic bullae that progress to ulceration. This case report describes a patient whose diagnosis of leprosy occurred in the presence of Lucius phenomenon. Late diagnosis and delay in the implementation of specific therapy contributed to a...
Clinical trial for uniform multidrug therapy for leprosy patients in Brazil (U-...
Cruz,Rossilene Conceição da Silva; Bührer-Sékula,Samira; Penna,Gerson Oliveira; Moraes,Maria Elisabete Amaral de; Gonçalves,Heitor de SáAbstract: BACKGROUND: The Clinical Trial for Uniform Multidrug Therapy for Leprosy Patients in Brazil (U-MDT/CT-BR), designed to evaluate the effectiveness of a six-months regimen, assessed the adverse effects caused by the drugs. OBJECTIVE: Describe adverse effects due to MDT in U-MDT/CT-BR, comparing the uniform regimen (U-MDT) to the current WHO regimen (R-MDT). Patients and methods: After operational classi...
Presence of Mycobacterium leprae genotype 4 in environmental waters in Northeas...
Holanda,Maísa Viana de; Marques,Livia Erika Carlos; Macedo,Maria Luisa Bezerra de; Pontes,Maria Araci de Andrade; Sabadia,José Antonio BeltrãoAbstract INTRODUCTION: This study quantified Mycobacterium leprae bacilli in environmental water samples from five municipalities in the State of Ceará by quantitative polymerase chain reaction (qPCR) and compared the identified genotypes with those obtained from leprosy patient biopsies. METHODS: We collected five replicas from each of the 30 selected reservoirs and skin lesion biopsies from 25 new leprosy cas...
Perfil clínico-epidemiológico dos pacientes diagnosticados com hanseníase em um...
Gomes,Cícero Cláudio Dias; Pontes,Maria Araci de Andrade; Gonçalves,Heitor de Sá; Penna,Gerson OliveiraFUNDAMENTOS: A hanseníase permanece sério problema de saúde pública mundial. O conhecimento das características epidemiológicas da doença é importante ferramenta para o controle da endemia. OBJETIVO: Descrever as características clínicas e epidemiológicas dos pacientes diagnosticados com hanseníase no ano de 2004 em um centro de referência da Região Nordeste do Brasil. MÉTODO: Foram avaliados prontuários de pac...