7 documents found, page 1 of 1

Balance Between Maternal Antiviral Response and Placental Transfer of Protectio...

The intricate interplay between maternal immune response to SARS-CoV-2 and the transfer of protective factors to the fetus remains unclear. By analyzing mother-neonate dyads from second and third trimester SARS-CoV-2 infections, our study shows that neutralizing antibodies (NAbs) are infrequently detected in cord blood. We uncovered that this is due to impaired IgG-NAb placental transfer in symptomatic infectio...

Code of Practice for Medical Autopsies: a Minimum Standard Position Paper for P...

The medical autopsy (also called hospital or clinical autopsy) is a highly specialised medical procedure, which requires professional expertise and suitably equipped facilities. To ensure high standards of performance, the Working Group of Autopsy Pathology of the European Society of Pathology (ESP) suggests a code of practice as a minimum standard for centres performing medical autopsies. The proposed standard...

Case Report: Rare Convexity Meningeal Chondroma Mimicking a Meningioma

Background: Intracranial chondromas account for 0.2-0.3% of all intracranial neoplastic lesions and less than a quarter arise in the convexity or falx. Despite its benign nature, exceedingly rare malignant transformations exist. The misdiagnosis with meningiomas is frequent and may be related with chondromas' similar insidious clinical presentation and imaging features. Standalone surgery is advised and complet...

Neuroenteric Cyst: a Rare Lesion of the Spinal Cord

BD-2 and BD-3 Increase Skin Flap Survival in a Model of Ischemia and Pseudomona...

The main aim of this work was to study the usefulness of human β-defensins 2 (BD-2) and 3 (BD-3), which are part of the innate immune system, in the treatment of infected ischemic skin flaps. We investigated the effect of transducing rat ischemic skin flaps with lentiviral vectors encoding human BD-2, BD-3, or both BD-2 and BD-3, to increase flap survival in the context of a P. aeruginosa infection associated w...

Simultaneous Supratentorial and Infratentorial Pilocytic Astrocytomas in an Adu...

BACKGROUND: Neurofibromatosis type 1 (NF1) has been identified as a predisposing factor in the development of pilocytic astrocytoma (PA), a common benign central nervous system tumor. Although this is a common association, simultaneous development of multiple lesions is an infrequent finding, especially in nonoptic and hypothalamic locations. CASE DESCRIPTION: A 41-year-old female patient with NF1 and uncontrol...

A Dissecação Como Ferramenta Pedagógica no Ensino da Anatomia em Portugal

Ao longo da História, a importância da utilização de cadáveres humanos para o ensino e investigação não tem sido consensual. No passado, a obtenção dos cadáveres indispensáveis ao ensino passou pelo recurso a cadáveres de reclusos, de não reclamados e ao roubo e/ou compra. Para além da inadmissibilidade ética e jurídica destas soluções, estas revelaram-se insuficientes para as necessidades das escolas médicas. ...