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HBM4EU e-waste study – Occupational exposure assessment to chromium, cadmium, m...

Leese, Elizabeth; Verdonck, Jelle; Porras, Simo P.; Airaksinen, Jaakko; Duca, Radu C.; Galea, Karen S.; Godderis, Lode; Janasik, Beata; Mahiout, Selma

Processing of electronic waste (e-waste) causes the release of toxic substances which may lead to occupational exposure. The study aimed to gather information on potential occupational exposure during e-waste recycling, with a focus on biomonitoring of chromium, cadmium, mercury and lead. In eight European countries, 195 workers involved in the recycling of lead batteries, white goods, brown goods and metals an...


How to use human biomonitoring in chemical risk assessment: Methodological aspe...

Santonen, Tiina; Mahiout, Selma; Alvito, Paula; Apel, Petra; Bessems, Jos; Bil, Wieneke; Borges, Teresa; Bose-O'Reilly, Stephan; Buekers, Jurgen

The need for such information is pressing, as previous research has indicated that regulatory risk assessors generally lack knowledge and experience of the use of HBM data in RA. By recognising this gap in expertise, as well as the added value of incorporating HBM data into RA, this paper aims to support the integration of HBM into regulatory RA. Based on the work of the HBM4EU, we provide examples of different...


HBM4EU e-waste study: Occupational exposure of electronic waste workers to phth...

Cleys, Paulien; Hardy, Emilie; Ait Bamai, Yu; Poma, Giulia; Cseresznye, Adam; Malarvannan, Govindan; Scheepers, Paul T.J.; Viegas, Susana

Workers involved in the processing of electronic waste (e-waste) are potentially exposed to toxic chemicals, including phthalates and alternative plasticizers (APs). Dismantling and shredding of e-waste may lead to the production of dust that contains these plasticizers. The aim of this study, which was part of the European Human Biomonitoring Initiative (HBM4EU), was to assess the exposure to phthalates (e.g. ...


How can multi-national occupational studies support policy making in Europe? Ex...

Santonen, Tiina; Louro, Henriqueta; Bocca, Beatrice; Bousoumah, Radia; Corneliu Duca, Radu; Fucic, Aleksandra; Galea, Karen S.; Godderis, Lode

Providing policy relevant data on chemical exposures was a major aim of the EU biomonitor-ing initiative, HBM4EU. Similarly, the recently launched “Partnership for the risk assessment of chemicals” (PARC) emphasizes the relevance of the research findings to regulatory deci-sion making. Occupational biomonitoring studies performed under HBM4EU were focused on HBM4EU priority substances with specific regulatory r...


HBM4EU chromates study: determinants of exposure to hexavalent chromium in plat...

Viegas, Susana; Martins, Carla; Bocca, Beatrice; Bousoumah, Radia; Duca, Radu Corneliu; Galea, Karen S.; Godderis, Lode; Iavicoli, Ivo; Janasik, Beata

Work-related exposures in industrial processing of chromate (chrome plating, surface treatment, and welding) raise concerns regarding the health risk of hexavalent chromium (Cr(VI)). In this study, performed under the HBM4EU project, we focused on better understanding the determinants of exposure and recognising how risk management measures (RMMs) contribute to a reduction in exposure. HBM and occupational hygi...


HBM4EU chromates study: overall results and recommendations for the biomonitori...

Santonen, Tiina; Porras, Simo P.; Bocca, Beatrice; Bousoumah, Radia; Duca, Radu Corneliu; Galea, Karen S.; Godderis, Lode; Göen, Thomas; Hardy, Emilie

Exposure to hexavalent chromium [Cr(VI)] may occur in several occupational activities, e.g., welding, Cr(VI) electroplating, and other surface treatment processes. The aim of this study was to provide EU-relevant data on occupational Cr(VI) exposure to support the regulatory risk assessment and decision-making. In addition, the capability and validity of different biomarkers for the assessment of Cr(VI) exposur...


HBM4EU chromates study: usefulness of measurement of blood chromium levels in t...

Ndaw, Sophie; Leso, Veruscka; Bousoumah, Radia; Rémy, Aurélie; Bocca, Beatrice; Duca, Radu Corneliu; Godderis, Lode; Hardy, Emilie; Janasik, Beata

Occupational exposures to hexavalent chromium (Cr(VI)) can occur in welding, hot working stainless steel processing, chrome plating, spray painting, and coating activities. Recently, within the human biomonitoring for Europe initiative (HBM4EU), a study was performed to assess the suitability of different biomarkers to assess the exposure to Cr(VI) in various job tasks. Blood-based biomarkers may prove useful w...


The HBM4EU chromates study - Outcomes and impacts on EU policies and occupation...

Santonen, Tiina; Louro, Henriqueta; Bocca, Beatrice; Bousoumah, Radia; Duca, Radu Corneliu; Fucic, Aleksandra; Galea, Karen S.; Godderis, Lode

Within the EU human biomonitoring initiative (HBM4EU), a targeted, multi-national study on occupational exposure to hexavalent chromium (Cr(VI)) was performed. Cr(VI) is currently regulated in EU under REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) and under occupational safety and health (OSH) legislation. It has recently been subject to regulatory actions to improve its risk mana...


HBM4EU Chromates Study: Determinants of Exposure to Hexavalent Chromium in Plat...

Viegas, Susana; Martins, Carla; Bocca, Beatrice; Bousoumah, Radia; Duca, Radu Corneliu; Galea, Karen S.; Godderis, Lode; Iavicoli, Ivo; Janasik, Beata

Work-related exposures in industrial processing of chromate (chrome plating, surface treatment and welding) raise concern regarding the health risk of hexavalent chromium (Cr(VI)). In this study, performed under the HBM4EU project, we focused on better understanding the determinants of exposure and recognising how risk management measures (RMMs) contribute to a reduction in exposure. HBM and occupational hygien...


HBM4EU chromates study - Usefulness of measurement of blood chromium levels in ...

Ndaw, Sophie; Leso, Veruscka; Bousoumah, Radia; Rémy, Aurélie; Bocca, Beatrice; Duca, Radu Corneliu; Godderis, Lode; Hardy, Emilie; Janasik, Beata

Occupational exposures to hexavalent Chromium (Cr(VI)) can occur in welding, hot working stainless steel processing, chrome plating, spray painting and coating activities. Recently, within the human biomonitoring for Europe initiative (HBM4EU), a study was performed to assess the suitability of different biomarkers to assess the exposure to Cr(VI) in various job tasks. Blood-based biomarkers may prove useful wh...


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