13 documents found, page 1 of 2
Brazilian Society of Hepatology and Brazilian Society of Infectious Diseases Gu...
Ferraz,Maria Lucia; Strauss,Edna; Perez,Renata Mello; Schiavon,Leonardo; Ono,Suzane Kioko; Pessoa,Mario Guimarães; Ferreira,Adalgisa PaivaAbstract Chronic hepatitis B is an important health problem that can progress to cirrhosis and complications such as hepatocellular carcinoma. There is approximately 290 million of people with chronic hepatitis B virus (HBV) infection worldwide, however only 10% of patients are currently identified.Most part of Brazil is considered of low prevalence of HBV infection but there are some regions with higher freque...
Decreased health-related quality of life in children and adolescents with autoi...
Bozzini,Ana Beatriz; Neder,Luciana; Silva,Clovis A.; Porta,GildaAbstract Objective: The objective of this study was to evaluate the health-related quality of life in children and adolescents with autoimmune hepatitis. Methods: A cross-sectional assessment with the Pediatric Quality of Life Inventory 4.0 (PedsQL 4.0) was completed for 80 patients with autoimmune hepatitis and 45 healthy controls. Demographic data, prednisone dose, disease remission state, disease severity, a...
Autoimmune hepatitis in 828 Brazilian children and adolescents: clinical and la...
Porta,Gilda; Carvalho,Elisa de; Santos,Jorge L.; Gama,Jorge; Borges,Cristian V.; Seixas,Renata B.P.M.; Ferreira,Alexandre R.; Miura,Irene K.Abstract Objective: This large study with a long-term follow-up aimed to evaluate the clinical presentation, laboratory findings, histological profile, treatments, and outcomes of children and adolescents with autoimmune hepatitis. Methods: The medical records of 828 children and adolescents with autoimmune hepatitis were reviewed. A questionnaire was used to collect anonymous data on clinical presentation, bio...
Lysosomal acid lipase deficiency in Brazilian children: a case series
Benevides,Gabriel Nuncio; Miura,Irene Kazue; Person,Natalia Canale; Pugliese,Renata Pereira Sustovich; Danesi,Vera Lúcia Baggio; Lima,Fabiana RobertoAbstract Objective: To describe the demographic, clinical, laboratory and molecular characteristics of patients with lysosomal acid lipase deficiency. Methods: A retrospective review of the medical records of children with the disease. Results: Seven children with lysosomal acid lipase deficiency (5 male; 2 female); 6 were mixed race, and 1 was black. The mean ages at the first onset of symptoms and at diagnosi...
Paracoccidioidomycosis in a liver transplant recipient
Lima,Thais Carneiro; Bezerra,Regis Otaviano Franca; Siqueira,Luiz Tenório de Brito; Menezes,Marcos Roberto de; Leite,Claudia da Costa; Porta,GildaABSTRACT Paracoccidioidomycosis is a granulomatous systemic mycosis that is endemic in Latin America; it is an extremely rare infection following solid organ transplantation. In this study, we describe the first report of disseminated paracoccidioidomycosis in a 3-year-old girl who underwent liver transplantation 2 years previously. The radiologic diagnosis and patient follow-up are described. In addition, we r...
Brazilian society of hepatology recommendations for the diagnosis and managemen...
Bittencourt,Paulo Lisboa; Cançado,Eduardo Luiz Rachid; Couto,Cláudia Alves; Levy,Cynthia; Porta,Gilda; Silva,Antônio Eduardo BeneditoABSTRACT In order to draw evidence-based recommendations concerning the management of autoimmune diseases of the liver, the Brazilian Society of Hepatology has sponsored a single-topic meeting in October 18th, 2014 at São Paulo. An organizing committee comprised of seven investigators was previously elected by the Governing Board to organize the scientific agenda as well as to select twenty panelists to make a ...
Epidemiological, serological and molecular aspects of hepatitis B and C in chil...
Ciaccia,Maria Célia Cunha; Moreira,Regina Célia; Lemos,Marcílio Figueiredo; Oba,Isabel Takano; Porta,GildaObjective: To estimate the prevalence of the serological markers anti-HBc, HBsAg and anti-HBs of hepatitis B and anti-HCV of hepatitis C among children and teenagers enrolled at daycare facilities, kindergartens and municipal elementary education network in the city of Santos, São Paulo, Brazil. Methods: A cross-sectional study was carried out from June 28 to December 14, 2007, in which 4,680 finger-prick blood...
Acute liver failure in a term neonate after repeated paracetamol administration
Bucaretchi,Fábio; Fernandes,Carla Borrasca; Branco,Maíra Migliari; Capitani,Eduardo Mello De; Hyslop,Stephen; Caldas,Jamil Pedro S.Objective: Severe hepatotoxicity caused by paracetamol is rare in neonates. We report a case of paracetamol-induced acute liver failure in a term neonate.Case description: A 26-day-old boy was admitted with intestinal bleeding, shock signs, slight liver enlargement, coagulopathy, metabolic acidosis (pH=7.21; bicarbonate: 7.1mEq/L), hypoglycemia (18mg/dL), increased serum aminotransferase activity (AST=4,039IU/L...
Hepatitis B virus infection in children, adolescents, and their relatives: geno...
Compri,Adriana Parise; Miura,Irene; Porta,Gilda; Lemos,Marcilio Figueiredo; Saraceni,Cláudia Patara; Moreira,Regina CéliaINTRODUCTION:The objectives of this study were evaluate hepatitis B virus (HBV) serological markers in children and adolescents followed up at the Child Institute of the Hospital das Clínicas, Faculdade de Medicina de São Paulo, Universidade de São Paulo; identify chronic HBV carriers and susceptible individuals in the intrafamilial environment; characterize HBV genotypes; and identify mutations in the patients...
Epidemiological and serological aspects of hepatitis A among children and teena...
Ciaccia,Maria Célia Cunha; Moreira,Regina Célia; Ferraro,Alexandre Archanjo; Lemos,Marcílio Figueiredo; Oba,Isabel Takano; Porta,GildaCONTEXT AND OBJECTIVE: Viral hepatitis A is still a concern at public health level in Brazil and around the world, due both to the number of affected subjects and the possibility of complications in the acute forms. The Brazilian Ministry of Health estimates that at least 70% of this country's population has already had contact with the hepatitis A virus (HAV). The aim here was to discover the prevalence of ser...