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Serum interleukin-17 levels are associated with nephritis in childhood-onset sy...

Peliçari, Karina de Oliveira; Postal, Mariana; Sinicato, Nailú Angelica; Peres, Fernando Augusto; Fernandes, Paula Teixeira; Marini, Roberto

OBJECTIVES: To determine the serum interleukin-17 (IL-17) levels in childhood-onset systemic lupus erythematosus patients and to evaluate the association between IL-17 and clinical manifestations, disease activity, laboratory findings and treatment. METHODS: We included 67 consecutive childhood-onset systemic lupus erythematosus patients [61 women; median age 18 years (range 11-31)], 55 first-degree relatives [...

Date: 2015   |   Origin: Oasisbr

Clinical and serological manifestations associated with interferon-α l...

Postal, Mariana; Sinicato, Nailu Angélica; Peliçari, Karina Oliveira; Marini, Roberto; Lavras Costallat, Lilian Tereza; Appenzeller, Simone

OBJECTIVE: To determine the serum levels of interferon alpha in childhood-onset systemic lupus erythematosus patients, their first-degree relatives and healthy controls and to evaluate the associations between serum interferon alpha and disease activity, laboratory findings and treatment features. METHODS: We screened consecutive childhood-onset systemic lupus erythematosus patients in a longitudinal cohort at ...

Date: 2012   |   Origin: Oasisbr

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