4 documents found, page 1 of 1
Association between levobupivacaine and pancuronium. Interference in neuromuscu...
Carvalho,Vanessa Henriques; Braga,Angélica de Fátima de Assunção; Braga,Franklin Sarmento da Silva; Potério,Gloria Maria BragaABSTRACT PURPOSE: To evaluate the effects of levobupivacaine on neuromuscular transmission and neuromuscular blockade produced by pancuronium in vitro. METHODS: Thirty rats were distributed into groups (n = 5) according to the drug used alone or in combination: Group I - levobupivacaine (5 µg.mL-1); Group II - pancuronium (2 µg.mL-1); Group III - pancuronium (2 µg.mL-1) + levobupivacaine (5µg.mL-1). The followi...
Effect of ropivacaine combined with pancuronium on neuromuscular transmission a...
Braga,Angélica de Fátima; Carvalho,Vanessa Henriques; Braga,Franklin Sarmento; Potério,Gloria Maria Braga; Santos,Filipe Nadir CaparicaBACKGROUND AND OBJECTIVES: The local anesthetic effects on neuromuscular junction and its influence on blockade produced by nondepolarizing neuromuscular blockers are still under-investigated; however, this interaction has been described in experimental studies and in humans. The aim of this study was to evaluate in vitro the interaction between ropivacaine and pancuronium, the influence on transmission and neu...
Evidence of presynaptic and postsynaptic action of local anesthetics in rats
Braga,Angélica de Fátima de Assunção; Carvalho,Vanessa Henriques; Braga,Franklin Sarmento da Silva; Potério,Gloria Maria BragaPURPOSE: To assess the probable actions of ropivacaine, 50% enantiomeric excess bupivacaine mixture (S75-R25) and levobupivacaine on neuromuscular transmission in vitro. METHODS: Thirty rats were distributed into groups (n=5) according to the drug used: ropivacaine, bupivacaine (S75-R25) and levobupivacaine. The concentration used for the three local anesthetics (LA) was 5 µg.mL.-1The following parameters were ...
Efeitos neuromusculares e cardiovasculares do pipecurônio: estudo comparativo e...
Braga,Angélica de Fátima de Assunção; Yoshioka,Leandro; Braga,Franklin Sarmento da Silva; Potério,Gloria Maria Braga; Frias,José Aristeu F.JUSTIFICATIVA E OBJETIVOS: O pipecurônio é um bloqueador neuromuscular não-despolarizante, com propriedades similares as do pancurônio, mas desprovido de efeitos cardiovasculares. Foram avaliados os efeitos neuromusculares, as condições de intubação traqueal e as repercussões hemodinâmicas de duas diferentes doses de pipecurônio. MÉTODO: Pacientes foram distribuídos em dois grupos de acordo com a dose de pipecu...