10 documents found, page 1 of 1
Quality of life associated with breathlessness in the multinational Burden of O...
Müller, Alexander; Wouters, Emiel F.; Burney, Peter; Potts, James; Cardoso, Joao; Al Ghobain, Mohammed; Studnicka, Michael; Obaseki, DanielIntroduction: Evidence of an association between breathlessness and quality of life from population-based studies is limited. We aimed to investigate the association of physical and mental quality of life with breathlessness across several low-, middle- and high-income countries. Methods: We analyzed data from 19,714 adults (31 sites, 25 countries) from the Burden of Obstructive Lung Disease (BOLD) study. We me...
Concordance between FVC and FEV<sub>6</sub> for identifying chronic airflow obs...
Knox-Brown, Ben; Potts, James; Franssen, Frits M. E.; Nielsen, Rune; Denguezli, Meriem; Rotevatn, Anders Ørskov; Juvekar, Sanjay K.Introduction: We investigated whether the forced expiratory volume in 6 s (FEV6) can be used as a surrogate for the forced vital capacity (FVC). Methods: The Burden of Obstructive Lung Disease is a multinational cohort study. At baseline, data were collected from adults aged 40 years or older, from 41 sites across 34 countries. Participants from 18 sites were followed up after a median of 8.3 years. Participant...
Geographical variation in lung function: results from the multicentric cross-se...
Burney, Peter G.; Potts, James; Knox-Brown, Ben; Erhabor, Gregory; Hacene Cherkaski, Hamid; Mortimer, Kevin; Anand, Mahesh Padukudru; Mannino, David M.Spirometry is used to determine what is "unusual" lung function compared with what is "usual" for healthy non-smokers. This study aimed to investigate regional variation in the forced vital capacity (FVC) and in the forced expiratory volume in one second to FVC ratio (FEV1/FVC) using cross-sectional data from all 41 sites of the multinational Burden of Obstructive Lung Disease study. Participants (5,368 men; 9,...
Prevalence of chronic cough, its risk factors and population attributable risk ...
Abozid, Hazim; Patel, Jaymini; Burney, Peter; Hartl, Sylvia; Breyer-Kohansal, Robab; Mortimer, Kevin; Nafees, Asaad A.; Al Ghobain, MohammedBackground: Chronic cough is a common respiratory symptom with an impact on daily activities and quality of life. Global prevalence data are scarce and derive mainly from European and Asian countries and studies with outcomes other than chronic cough. In this study, we aimed to estimate the prevalence of chronic cough across a large number of study sites as well as to identify its main risk factors using a stan...
Geographical variation in lung function: results from the multicentric cross-se...
Burney, Peter G. J.; Potts, James; Knox-Brown, Ben; Erhabor, Gregory; Hacene Cherkaski, Hamid; Mortimer, Kevin; Anand, Mahesh PadukudruSpirometry is used to determine what is "unusual" lung function compared with what is "usual" for healthy non-smokers. This study aimed to investigate regional variation in the forced vital capacity (FVC) and in the forced expiratory volume in one second to FVC ratio (FEV1/FVC) using cross-sectional data from all 41 sites of the multinational Burden of Obstructive Lung Disease study. Participants (5,368 men; 9,...
Prevalence of chronic cough, its risk factors and population attributable risk ...
Abozid, Hazim; Patel, Jaymini; Burney, Peter; Hartl, Sylvia; Breyer-Kohansal, Robab; Mortimer, Kevin; Nafees, Asaad A.; Al Ghobain, MohammedBackground: Chronic cough is a common respiratory symptom with an impact on daily activities and quality of life. Global prevalence data are scarce and derive mainly from European and Asian countries and studies with outcomes other than chronic cough. In this study, we aimed to estimate the prevalence of chronic cough across a large number of study sites as well as to identify its main risk factors using a stan...
Small airways obstruction and its risk factors in the Burden of Obstructive Lun...
Knox-Brown, Ben; Patel, Jaymini; Potts, James; Ahmed, Rana; Aquart-Stewart, Althea; Cherkaski, Hamid Hacene; Denguezli, Meriam; Elbiaze, MohammedBackground: Small airway obstruction is a common feature of obstructive lung diseases. Research is scarce on small airway obstruction, its global prevalence, and risk factors. We aimed to estimate the prevalence of small airway obstruction, examine the associated risk factors, and compare the findings for two different spirometry parameters. Methods: The Burden of Obstructive Lung Disease study is a multination...
Small airways obstruction and its risk factors in the Burden of Obstructive Lun...
Knox-Brown, Ben; Patel, Jaymini; Potts, James; Ahmed, Rana; Aquart-Stewart, Althea; Cherkaski, Hamid Hacene; Denguezli, Meriam; Elbiaze, MohammedBackground: Small airways obstruction is a common feature of obstructive lung diseases. Research is scarce on small airways obstruction, its global prevalence, and risk factors. We aimed to estimate the prevalence of small airways obstruction, examine the associated risk factors, and compare the findings for two different spirometry parameters. Methods: The Burden of Obstructive Lung Disease study is a multinat...
COPD: should diagnosis match physiology?
Studnicka, Michael; Horner, Andreas; Sator, Lea; Buist, A. Sonia; Lamprecht, Bernd; Zhong, NanShan; Liu, Shengming; Lu, Jiachun; Ran, Pixin; Wang, DaliWe are very grateful to Dr. Vanfleteren and colleagues for commenting on our data regarding overdiagnosed COPD2 and for putting this evidence into the framework of the current understanding of the disease. Based on the data presented on overdiagnosis, and on prior Burden of Obstructive Lung Disease (BOLD) observations on underdiagnosis,3 we truly believe that our worldwide community of pulmonary specialists cou...
Overdiagnosis of COPD in subjects with unobstructed spirometry
Sator, Lea; Horner, Andreas; Studnicka, Michael; Lamprecht, Bernd; Kaiser, Bernhard; McBurnie, Mary Ann; Buist, A. Sonia; Gnatiuc, LuisaBackground: There are several reports on the underdiagnosis of COPD, while little is known about COPD overdiagnosis and overtreatment. We describe the overdiagnosis and the prevalence of spirometrically defined false-positive COPD, as well as their relationship with overtreatment across 23 population samples in 20 countries participating in the BOLD Study between 2003 and 2012. Methods: A false-positive diagnos...