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Targeted Reinforcement of Macrophage Reprogramming Toward M2 Polarization by IL...

Shahbazi, M; Sedighi, M; Bauleth-Ramos, T; Kant, K; Correia, A; Poursina, N; Sarmento, B; Hirvonen, J; Santos, H

Alteration of macrophage polarization from inflammatory (M1) to anti-inflammatory (M2) phenotype can have striking implications for the regeneration of injured tissues, treatment of inflammatory diseases, and relief of autoimmune disorders. Although certain cytokines like interleukin (IL)-4 and IL-13 are capable of inducing M2 macrophage polarization, their therapeutic potential in vivo is suffering from low ef...


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