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The Association Between Hepatitis B Virus Infection and Nonliver Malignancies i...

Mocroft, A; Miro, J; Wandeler, G; Llibre, J; Boyd, A; van Bremen, K; Beniowski, M; Mikhalik, J; Cavassini, M; Maltez, F; Duvivier, C; Uberti Foppa, C

Objectives: The aim of this study was to assess the impact of hepatitis B virus (HBV) infection on non-liver malignancies in people living with HIV (PLWH). Methods: All persons aged ≥ 18 years with known hepatitis B virus (HBV) surface antigen (HBsAg) status after the latest of 1 January 2001 and enrolment in the EuroSIDA cohort (baseline) were included in the study; persons were categorized as HBV positive or ...


Correction to: Clinical management of ageing people living with HIV in Europe: ...

Boffito, M; Ryom, L; Spinner, C; Martinez, E; Behrens, G; Rockstroh, J; Hohenauer, J; Lacombe, K; Psichogyiou, M; Voith, N; Mallon, P; Branco, T, et al.


Clinical management of ageing people living with HIV in Europe: the view of the...

Boffito, M; Ryom, L; Spinner, C; Martinez, E; Behrens, G; Rockstroh, J; Hohenauer, J; Lacombe, K; Psichogyiou, M; Voith, N; Mallon, P; Branco, T, et al.

BACKGROUND: Although guidelines for the management of HIV infection include recommendations for aging people living with HIV (PLWH), clinical practice of European HIV care providers may vary. METHOD: We performed a study using a 3-phase Delphi methodology by involving a panel of clinicians with expertise in HIV infection clinical management. The main aim of the study was to assess the care provider prospective ...


Lipodystrophy defined by Fat Mass Ratio in HIV-infected patients is associated ...

Freitas, P; Carvalho, D; Santos, AC; Mesquita, J; Matos, MJ; Madureira, AJ; Martinez, E; Sarmento, A; Medina, JL

Introduction: Combined antiretroviral therapy (cART) in the treatment of HIV-1 infection has been associated with complications, including lipodystrophy, hyperlipidaemia, insulin resistance (IR) and diabetes.Aims: To compare the prevalence of glucose homeostasis disturbances and IR in HIV patients on cART according to the presence of lipodystrophy (defined clinically and by Fat Mass Ratio) and different pattern...


Central/peripheral fat mass ratio is associated with increased risk of hyperten...

Freitas, P; Carvalho, D; Santos, AC; Madureira, AJ; Xerinda, S; Martinez, E; Pereira, J; Sarmento, A; Medina, JL

The data on the risk of hypertension in human immunodeficiency virus (HIV)-infected patients, particularly in those with lipodystrophy, are controversial. The authors assessed the impact of lipodystrophy on hypertension in a cohort of HIV-infected adults receiving combination antiretroviral therapy. This was a cross-sectional study in which lipodystrophy (clinically and fat mass ratio [FMR]-defined), blood pres...


Prevalence of obesity and its relationship to clinical lipodystrophy in HIV-inf...

Freitas, P; Carvalho, D; Santos, AC; Matos, MJ; Madureira, AJ; Marques, R; Martinez, E; Sarmento, A; Medina, JL

Background: Combination antiretroviral therapy (cART) is associated with lipodystrophy (lipoatrophy and lipoaccumulation) and several metabolic abnormalities that together can contribute to an increased cardiovascular risk. The aim of this study was to evaluate the prevalence of obesity in patients on cART according to the presence of clinical lipodystrophy (CL) and to analyze factors associated with obesity. M...


Impact of Lipodystrophy on the prevalence and components of metabolic syndrome ...

Freitas, P; Carvalho, D; Souto, S; Santos, AC; Xerinda, S; Marques, R; Martinez, E; Sarmento, A; Medina, JL

Background: In HIV-infected patients, combination antiretroviral therapy (cART) is associated with clinical lipodystrophy (CL) and metabolic abnormalities (MA). This study aimed to evaluate the prevalence of the metabolic syndrome (MS) and its components, and to determine whether patients with or without CL had a different prevalence of MA.Methods: We evaluated 345 HIV-infected patients on cART using two differ...


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