2 documents found, page 1 of 1
Renin-Angiotensin System Blockade Associated with Statin Improves Endothelial F...
Gismondi,Ronaldo Altenburg; Bedirian,Ricardo; Pozzobon,Cesar Romaro; Ladeira,Márcia Cristina; Oigman,Wille; Neves,Mário FritschAbstract Background: Studies suggest that statins have pleiotropic effects, such as reduction in blood pressure, and improvement in endothelial function and vascular stiffness. Objective: To analyze if prior statin use influences the effect of renin-angiotensin-aldosterone system inhibitors on blood pressure, endothelial function, and vascular stiffness. Methods: Patients with diabetes and hypertension with off...
Functional Vascular Study in Hypertensive Subjects with Type 2 Diabetes Using L...
Pozzobon,Cesar Romaro; Gismondi,Ronaldo A. O. C.; Bedirian,Ricardo; Ladeira,Marcia Cristina; Neves,Mario Fritsch; Oigman,WilleBackground: Antihypertensive drugs are used to control blood pressure (BP) and reduce macro- and microvascular complications in hypertensive patients with diabetes. Objectives: The present study aimed to compare the functional vascular changes in hypertensive patients with type 2 diabetes mellitus after 6 weeks of treatment with amlodipine or losartan. Methods: Patients with a previous diagnosis of hypertension...