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Circadian variation of fatigue in both patients with paralytic poliomyelitis an...
Viana,Celiana Figueiredo; Pradella-Hallinan,Márcia; Quadros,Abrahão Augusto Juviniano; Marin,Luis Fabiano; Oliveira,Acary Souza BulleObjectiveIt was to evaluate the degree of fatigue in patients with paralytic poliomyelitis (PP) and with post-polio syndrome (PPS), and correlate it with parameters of sleep and the circadian cycle.MethodsThirty patients, 17 female (56.7%), participated in the study: they answered the Revised Piper Fatigue Scale and performed a nocturnal polysomnographic study. Eleven had PP (mean age±standard deviation of 47.9...
Effects of Dăoyĭn Qìgōng in postpolio syndrome patients with cold intolerance
Ramos,Paulo Eduardo; Abe,Gislaine Cristina; Pradella-Hallinan,Márcia; Quadros,Abrahão Augusto Juviniano; Schmidt,Beny; Oliveira,Acary Souza BullePostpolio syndrome (PPS) is characterized by progressive muscle weakness due to former infection with poliomyelitis and can be associated with other symptoms such as cold intolerance (CI). Dăoyĭn Qìgōng (DQ) is a technique in Traditional Chinese Medicine that impacts the circulation of energy and blood. OBJECTIVE: It was to verify the effects of DQ in PPS patients complaining of cold intolerance. METHODS: Ten P...
Sleep disorders frequency in post-polio syndrome patients caused by periodic li...
Araujo,Maria Auxiliadora de Paiva; Silva,Tatiana Mesquita e; Moreira,Gustavo Antonio; Pradella-Hallinan,Márcia; Tufik,Sergio; Oliveira,Acary Souza BullePost-polio syndrome (PPS) in individuals with polio longer than 15 years is characterized by weakness and/or muscle fatigue, deficit of deglutition and breath and periodic limb movements (PLM) during sleep. We undertook a review of 99 patients with PPS, and assessed the frequency of PLM through polysomnographic recordings at our sleep disorders unit. The total number of PLM, total time of sleep (TTS), efficienc...
Analysis of sleep characteristics in post-polio syndrome patients
Silva,Tatiana Mesquita e; Moreira,Gustavo Antonio; Quadros,Abrahão Augusto Juviniano; Pradella-Hallinan,Márcia; Tufik,Sergio; Oliveira,Acary Souza BulleThe main post-polio syndrome (PPS) symptoms are new weakness, new atrophy, fatigue, pain and sleep disturbances. Polysomnography is the gold standard for sleep analysis. OBJECTIVE: To analyze sleep patterns in PPS patients. METHOD: Sixty patients (mean age 46.8±11.3 years) at the Federal University of São Paulo (UNIFESP/EPM) complaining of sleep disturbances were evaluated by means of polysomnography, performed...
New guidelines for diagnosis and treatment of insomnia
Pinto Jr,Luciano Ribeiro; Alves,Rosana Cardoso; Caixeta,Eliazor; Fontenelle,John Araujo; Bacellar,Andrea; Poyares,Dalva; Aloe,Flavio; Rizzo,GeraldoThe Brazilian Sleep Association brought together specialists in sleep medicine, in order to develop new guidelines on the diagnosis and treatment of insomnias. The following subjects were discussed: concepts, clinical and psychosocial evaluations, recommendations for polysomnography, pharmacological treatment, behavioral and cognitive therapy, comorbidities and insomnia in children. Four levels of evidence were...
Traditional biomarkers in narcolepsy: experience of a Brazilian sleep centre
Coelho,Fernando Morgadinho Santos; Pradella-Hallinan,Márcia; Pedrazzoli,Mario; Soares,Carlos Augusto Senne; Fernandes,Gustavo Bruniera PeresThis study was thought to characterized clinical and laboratory findings of a narcoleptic patients in an out patients unit at São Paulo, Brazil. METHOD: 28 patients underwent polysomnographic recordings (PSG) and Multiple Sleep Latency Test (MSLT) were analyzed according to standard criteria. The analysis of HLADQB1*0602 allele was performed by PCR. The Hypocretin-1 in cerebral spinal fluid (CSF) was measured u...
Diretrizes brasileiras para o tratamento da narcolepsia
Alóe,Flávio; Alves,Rosana Cardoso; Araújo,John F.; Azevedo,Alexandre; Bacelar,Andrea; Bezerra,Márcio; Bittencourt,Lia Rita Azeredo; Bustamante,GuilhermeEste artigo relata as conclusões da reunião de consenso da Associação Brasileira de Sono com médicos especialistas brasileiros sobre o tratamento da narcolepsia, baseado na revisão dos artigos sobre narcolepsia publicados entre 1980 e 2010. Os objetivos do consenso são valorizar o uso de agentes avaliados em estudos randomizados placebo-controlados, emitir recomendações de consenso para o uso de outras medicaçõ...
Diretrizes brasileiras para o diagnóstico de narcolepsia
Alóe,Flávio; Alves,Rosana Cardoso; Araújo,John F.; Azevedo,Alexandre; Bacelar,Andrea; Bezerra,Márcio; Bittencourt,Lia Rita Azeredo; Bustamante,GuilhermeEste artigo relata as conclusões da reunião de consenso com médicos especialistas sobre diagnóstico de narcolepsia baseada na revisão dos artigos sobre narcolepsia listados no Medline entre 1980 e 2010. A narcolepsia é uma doença crônica de início entre a primeira e segunda décadas de vida do indivíduo. Os sintomas essenciais são cataplexia e sonolência excessiva. A cataplexia é definida como episódios súbitos,...
Effects of the use of MIG3 bioceramics fabrics use - long infrared emitter - in...
Silva,Tatiana Mesquita e; Moreira,Gustavo Antonio; Quadros,Abrahão Augusto Juviniano; Pradella-Hallinan,Márcia; Tufik,Sergio; Oliveira,Acary Souza BulleThe main post-polio syndrome (PPS) symptoms are new-onset weakness, new-onset atrophy, fatigue, cold intolerance, and pain associated with sleep disturbances. The polysomnographic study is the gold pattern to analyze sleep disorders. OBJECTIVE: To assess pain, intolerance to cold and periodic limb movements (PLM) index before and after the use of MIG3 bioceramic fabrics over 4 weeks. METHOD: 12 patients with PP...
Prevalence of the HLA-DQB1*0602 allele in narcolepsy and idiopathic hypersomnia...
Coelho,Fernando Morgadinho Santos; Pradella-Hallinan,Márcia; Predazzoli Neto,Mario; Bittencourt,Lia Rita Azeredo; Tufik,SérgioOBJECTIVE: Narcolepsy (with and without cataplexy) and idiopathic hypersomnia, are disorders with common features but with different HLA-DQB1*0602 allele prevalence. The present study describes the prevalence of HLA-DQB1*0602 allele in narcoleptics with and without cataplexy and in patients with idiopathic hypersomnia. METHOD: Subjects comprised 68 patients who were diagnosed for narcolepsy or idiopathic hypers...